Protein Alignment CG8545 and nsun-1

DIOPT Version :10

• Sequence 1: NP_610786.2
• Gene: CG8545 / 36365
• FlyBaseID: FBgn0033741
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_493742.1
• Gene: nsun-1 / 173437
• WormBaseID: WBGene00021073
• Length: 664
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 307/710 - (43%)
• Similarity: 426/710 - (60%)
• Gaps: 78/710 - (10%)

  Fly   113 KGQKATAPKGFTDDNDAWLKP--KKQQKQPETESEEEEEEDEESEEDSEDELGEECEEEEEGDDE 175
            |.:.:.|.|..|:      ||  ||..|:|..|:|....:.::..:..:       :..::..:|
 Worm     6 KKKVSAASKAATE------KPEVKKAVKRPVAETEAVTPKKKKLVKKVK-------KSAKKAHEE 57

  Fly   176 EGLESDDDTAQVGKLADLSDDDDANSDDDFDISGEEDGAQADSDEEEDEDDDDDDDDDDDDKLPI 240
            |.:|      ||.||..:.||:|          |.|..:...||:|:..||..|||.|..|.|||
 Worm    58 EPIE------QVEKLQLIDDDED----------GLEGLSFPGSDDEDLRDDYSDDDSDAGDHLPI 106

  Fly   241 ERANKKLKKREAEEAQLADDEMLETVDKQDVFQLPVEGEETEKDL----TLQEVQQRIKDVSLVL 301
            |:.:..|.|::.:.....::|:...:..|..|:||.. ||.|.::    .|:.|:|||.||..||
 Worm   107 EKKSAALDKQKEKIIAEGEEELQLNIANQATFELPTV-EEIENEMKSVPNLEIVKQRIADVIQVL 170

  Fly   302 SDFKRYRQADRSRGEYIDLLRRDLCLYYSYNEFLMEKLMDMLPL-TELMEYLEASEIARPLTIRT 365
            .|||..|...:||..|:::|::|||..|.||::||.|.||:.|. .||:|:|||::..||:|||.
 Worm   171 GDFKNRRDPQKSRENYVEVLKKDLCSQYGYNDYLMGKFMDLFPNGAELLEFLEANDNPRPVTIRA 235

  Fly   366 NTLKTRRRDLAGALINRGVNLDPLGKWTKVGLVVFNSQVPLGATPEYLAGHYMIQGASSLLPVMA 430
            |:||.:|||||..|||||:|:||...||||||||::||||:|||||||||||||||.:|||||||
 Worm   236 NSLKVKRRDLAKNLINRGMNVDPAADWTKVGLVVYDSQVPVGATPEYLAGHYMIQGLNSLLPVMA 300

  Fly   431 LAPQENERILDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIVANFHRLGIVNAVVSCEDG 495
            ||||..:|:||||||||||.||||::|||:|||||||:|..|.:||:.|.||||:.|.||....|
 Worm   301 LAPQPGDRVLDMCSAPGGKTSHIAALMKNSGVLFANDANFTRCRAIIGNLHRLGVNNTVVCNLGG 365

  Fly   496 TKFRNIM-TGFDRVLLDAPCTGTGVVSKDPSVKTTKSEVDVQRCYNLQRKLLLTAIDCTDAKSST 559
            .:|..|. .||||:||||||:||||:.||.||||:|...||||.:.:||:|:|:|:|..||.|..
 Worm   366 EEFSKIRPNGFDRILLDAPCSGTGVIWKDQSVKTSKDSQDVQRRHTMQRQLILSALDSLDANSPN 430

  Fly   560 GGYIVYSTCSVLPEENEWVIDYALKKRNVKLVPTGLDFGVEGFTKFRQHRFHPSLNLTKRYYPHT 624
            |||:||||||||.||||.|:::.|::|:.:||||||..||:|:|:||.:||||||::|||||||.
 Worm   431 GGYLVYSTCSVLVEENEAVVNFLLERRHCELVPTGLSIGVDGYTRFRDYRFHPSLSMTKRYYPHV 495

  Fly   625 HNMDGFYVAKLKKFSNTIPITKEQQEEDEKQLDEAIEADATTEAAAESEEVEEEVASKEKGPRKL 689
            ||:|||||||:||.||. .::|:...|.||:.......:...:|.||:.|..::...|:.|
 Worm   496 HNIDGFYVAKIKKLSNA-KMSKQGVMEKEKEKAAQKSQNKKNKAEAEASESSDDEEEKKNG---- 555

  Fly   690 LGKRAGKPSFTEIEQELKKKKREESKTKYVAKVFEQPVKKPKPEKPAEKKNEKSQAPDKQTNSS- 753
                      .|:..:.|..|:::.|               |.:...:..::.:.||.|...|.
 Worm   556 ----------VEVNGQKKPAKKQQQK---------------KQKADGDDSDDDNNAPMKNIGSGA 595

  Fly   754 ------ESPSKSAPKQ---KQTNGKTTVSNSDAKSFNKKNKGSQPKENGAGSPAKPDDNK 804
                  .:..|:|.||   |:.:|..||.|........:.|...||...|.:.||...|:
 Worm   596 RANKKRRNQKKAAEKQAAVKEDDGFNTVGNVKRAKKPTQFKSKVPKRAAARTGAKSVKNR 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8545	NP_610786.2	nop2p	363..637	CDD:188051	182/274 (66%)
		PRK13808	<745..886	CDD:172341	20/70 (29%)
nsun-1	NP_493742.1	nop2p	233..508	CDD:188051	182/274 (66%)