Protein Alignment CG8545 and LOC1274929

DIOPT Version :10

• Sequence 1: NP_610786.2
• Gene: CG8545 / 36365
• FlyBaseID: FBgn0033741
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_314123.5
• Gene: LOC1274929 / 1274929
• VectorBaseID: AGAMI1_001702
• Length: 822
• Species: Anopheles gambiae
• Alignment Length: 918
• Identity: 451/918 - (49%)
• Similarity: 569/918 - (61%)
• Gaps: 145/918 - (15%)

  Fly     1 MGRKAEYSEKPKKGPGRKARKQGPPVFRKQSFAPMEEED--KKLSHRQKQRFVKREQKKVVQKAK 63
            ||||... |:||||||||||||..|.|:   |...|:||  ||||..|.||..|||..|..||
Mosquito     1 MGRKINL-ERPKKGPGRKARKQPEPEFQ---FKKGEDEDSNKKLSRHQIQRLKKREMLKQKQK-- 59

  Fly    64 LQEKRAKGKLPQPAKRKTAYNSDSDP------EDNEEEPQVASSDEEVPQLVPAPKGQKATAPKG 122
             :||:.| |..:.|.:..|..:..||      |.:.::.|......:.||.|.....|..:|.||
Mosquito    60 -EEKKTK-KATKNAAKVAAVPNTFDPAEIFNIEKSRQKYQQLGQKSKTPQPVATNGHQNGSAKKG 122

  Fly   123 ---FTDDND-----------AWLKPKKQQKQPETESEEEEEEDEESEEDSEDELGEECEEEEEGD 173
               |..||:           ..::.||.|.:...:..|.|:|.:..||:.:.::.|  ||:||.:
Mosquito   123 RNLFDSDNEMDEDEQKAATGKKVQVKKSQMKKFLQRAESEDESDSEEEEMDSDVEE--EEDEEAE 185

  Fly   174 DEEGLESDDDTAQVG-KLADLSDDDDANSDDDFDISGEEDGAQADSDEEEDEDDDDDDDDDDDDK 237
            ..||.|.|.:...|| :|.|..:||:..:::|:     ||..:.|.||:||| ||||:||:|.|.
Mosquito   186 SVEGEEDDYEDEDVGEELDDEEEDDEMGAEEDY-----EDDDEDDEDEDEDE-DDDDEDDEDGDM 244

  Fly   238 LPIERANKKLKKREAEEAQLADDEMLETVDKQDVFQLPVEGEETEKDLTLQEVQQRIKDVSLVLS 302
            ||||.||||||||...|.:.||.||.|....::.|..|.| ||..:..:||:|..|||||..|||
Mosquito   245 LPIEAANKKLKKRMEREQKEADAEMAEAAVNRERFAFPTE-EELAQTTSLQDVNMRIKDVVGVLS 308

  Fly   303 DFKRYRQADRSRGEYIDLLRRDLCLYYSYNEFLMEKLMDMLPLTELMEYLEASEIARPLTIRTNT 367
            ||...|..:|||.|||||||||||||||||:|.|..||::....||:|:||||||.||:|||||:
Mosquito   309 DFAANRDPNRSRCEYIDLLRRDLCLYYSYNDFFMGLLMEIFSPNELLEFLEASEIQRPVTIRTNS 373

  Fly   368 LKTRRRDLAGALINRGVNLDPLGKWTKVGLVVFNSQVPLGATPEYLAGHYMIQGASSLLPVMALA 432
            |||||||||.||||||:||||:|||:|.||||:.|||||||||||||||||:||.||:|||||||
Mosquito   374 LKTRRRDLAQALINRGINLDPIGKWSKEGLVVYTSQVPLGATPEYLAGHYMLQGGSSMLPVMALA 438

  Fly   433 PQENERILDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIVANFHRLGIVNAVVSCEDGTK 497
            |:|||||||||:|||||.||||::||||||||.||:|::|:.|::.|||||||.|||::|.||.|
Mosquito   439 PEENERILDMCAAPGGKSSHIAALMKNTGVLFVNDANKERLHAVLGNFHRLGIQNAVITCMDGVK 503

  Fly   498 FRNIMTGFDRVLLDAPCTGTGVVSKDPSVKTTKSEVDVQRCYNLQRKLLLTAIDCTDAKSSTGGY 562
            :.|||.|||||||||||||:||:|||||||.||:|:|||||:||||:||||||||..|.|.||||
Mosquito   504 YGNIMKGFDRVLLDAPCTGSGVISKDPSVKATKNEIDVQRCFNLQRRLLLTAIDCLSASSPTGGY 568

  Fly   563 IVYSTCSVLPEENEWVIDYALKKRNVKLVPTGLDFGVEGFTKFRQHRFHPSLNLTKRYYPHTHNM 627
            :||||||:||:|||||||:|||:|||:||||||||||||.|.|..|||||::.||:|:||||||:
Mosquito   569 LVYSTCSILPQENEWVIDFALKRRNVRLVPTGLDFGVEGMTSFGAHRFHPTMKLTRRFYPHTHNL 633

  Fly   628 DGFYVAKLKKFSNTIPITKEQQEEDEKQLDEAIEADATTEAAAESEEVEEEVASKEKGPRKLLGK 692
            |||:||||:|||:.||          |.:|...||:         :|||||...:.|.|:| :.|
Mosquito   634 DGFFVAKLQKFSDAIP----------KSVDGEPEAE---------DEVEEEPEEEMKLPKK-IDK 678

  Fly   693 RAGKPSFTEIEQELKKKKREESKTKYVAKVFEQP--VKK--PKPEKPAEKKNEKSQAPDKQTNSS 753
            |..  .:.:|..| :|.:||:....:|..||::|  |||  .||::|.....|:.|.|.|
Mosquito   679 RDW--YYQDIIDE-RKAQREDKNKNHVVTVFQKPANVKKGPKKPKQPQPSAGEREQKPQK----- 735

  Fly   754 ESPSKSAPKQKQTNGKTTVSNSDAKSFNKKNKGSQPKENGAGSPAKPDDNKPTTNGTNSPSKSAI 818
              |:...|||                                         |.||||:|.||
Mosquito   736 --PASEEPKQ-----------------------------------------PATNGTSSSSK--- 754

  Fly   819 KETKTKPQPKGKQSPKGNAKLAKAPRVDIDDVPILEGKPIKKQNKLKQKSKQIGQLKKSTAGANA 883
                 :.||    :||.|.                |.:..::..:||:|.||: |.|...||. .
Mosquito   755 -----QRQP----APKSNT----------------EQREAEEALRLKKKLKQV-QTKNGKAGP-G 792

  Fly   884 GKKQKFKK 891
            |||...||
Mosquito   793 GKKNGEKK 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8545	NP_610786.2	nop2p	363..637	CDD:188051	212/273 (78%)
		PRK13808	<745..886	CDD:172341	30/140 (21%)
LOC1274929	XP_314123.5	None