Protein Alignment Lac and Igsf9

DIOPT Version :9

• Sequence 1: NP_523713.2
• Gene: Lac / 36363
• FlyBaseID: FBgn0010238
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_001139272.1
• Gene: Igsf9 / 93842
• MGIID: 2135283
• Length: 1179
• Species: Mus musculus
• Alignment Length: 281
• Identity: 72/281 - (25%)
• Similarity: 109/281 - (38%)
• Gaps: 36/281 - (12%)

  Fly    69 PVFLSTGSTLVIKDSRFSLRYDPN-------SSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAE 126
            |:|:..|        .:|.|.||:       .:...|||:.::..|.|.|.|:|:....|....:
Mouse    65 PIFIQFG--------LYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQD 121

  Fly   127 ------VKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYV 185
                  |.|:|..||...:.....:...|...|.:.|.|.|.|.|.:||:.....:........|
Mouse   122 FANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVARGSPQPYVTWKFRGQDLGKGQGQVQV 186

  Fly   186 GN-TLRIKSVKKEDRGTYYCVADNGVSKGD-RRNINVEVEFAPVITVPRPRLGQALQYDMDLECH 248
            .| ||.|:.|::...|.|.|.|.:  |:|. .....:.|...|||.||..........|:.|.|.
Mouse   187 QNGTLWIRRVERGSAGDYTCQASS--SEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACR 249

  Fly   249 IEAYPPP-AIVWTKDDIQLANNQHYSISHFATADE-YTDSTLRVITVEKRQYGDYVCKATNRF-- 309
            .||||.. ...|.:|.:.:     :.||...:... ..|.:|.:...:....|.|.|..:|.|
Mouse   250 AEAYPANLTYSWFQDGVNV-----FHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLH 309

  Fly   310 -GEAEARVN-LFETIIPVCPP 328
             ..|.|.:. |:...:.|.||
Mouse   310 PPSASAYLTVLYPAQVTVMPP 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lac	NP_523713.2	IG_like	36..131	CDD:214653	18/74 (24%)
		FR1	37..50	CDD:409353
		Ig strand A'	37..42	CDD:409353
		Ig strand B	44..51	CDD:409353
		CDR1	51..59	CDD:409353
		Ig strand C	59..63	CDD:409353
		FR2	60..63	CDD:409353
		CDR2	67..81	CDD:409353	3/11 (27%)
		Ig strand C'	68..72	CDD:409353	1/2 (50%)
		Ig strand C'	79..81	CDD:409353	0/1 (0%)
		FR3	84..115	CDD:409353	11/37 (30%)
		Ig strand D	84..90	CDD:409353	2/5 (40%)
		Ig strand E	94..102	CDD:409353	3/7 (43%)
		Ig strand F	108..115	CDD:409353	3/6 (50%)
		CDR3	116..124	CDD:409353	1/7 (14%)
		FR4	124..130	CDD:409353	1/11 (9%)
		Ig strand G	124..130	CDD:409353	1/11 (9%)
		Ig_3	134..208	CDD:404760	21/74 (28%)
		Ig strand B	153..157	CDD:409353	1/3 (33%)
		Ig strand C	166..170	CDD:409353	1/3 (33%)
		Ig strand E	187..191	CDD:409353	3/4 (75%)
		Ig strand F	201..206	CDD:409353	2/4 (50%)
		Ig strand G	215..218	CDD:409353	0/2 (0%)
		Ig	227..318	CDD:416386	24/96 (25%)
		Ig strand C	256..260	CDD:409353	0/3 (0%)
		Ig strand E	286..290	CDD:409353	1/3 (33%)
		Ig strand F	300..305	CDD:409353	2/4 (50%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	14/52 (27%)
		Ig	136..223	CDD:386229	22/88 (25%)
		Ig_3	227..305	CDD:372822	21/82 (26%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I11062
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900