DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and zgc:152904

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001070212.1 Gene:zgc:152904 / 767777 ZFINID:ZDB-GENE-060929-856 Length:809 Species:Danio rerio


Alignment Length:257 Identity:64/257 - (24%)
Similarity:115/257 - (44%) Gaps:38/257 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 NSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQME 156
            |.....|.:|:|::||.|.|.|: ..:......:::.|.|...|.|:  ..::|.|.|||...:.
Zfish   232 NGGKSTLTVKNIKQTDGGPYMCR-ASNKAGSSESQLFLKVFVQPHIT--QLRNVTAVEGSAAMIS 293

  Fly   157 CYASGYPTPTITWRRENNAILPTDS-----------ATYVGNTLRIKSVKKEDRGTYYCVADNGV 210
            |.|.|.|.|.|:|||.::....||.           ..:..:.|.|..|:..|.|.:.|.|.:.:
Zfish   294 CTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDCEALSRI 358

  Fly   211 SKGDRRNINVEVEFAPVITVPRPRLGQALQYD-----MDLECHIEAYPPPAIVWTKDDIQLANNQ 270
            . |.::::.:::|:|     |:.:..|::.|.     :::.|.:::.|...::|.:        :
Zfish   359 G-GHQKSMFLDIEYA-----PKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRR--------E 409

  Fly   271 HYSISHFATAD---EYTD--STLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCP 327
            .::||...|::   ..||  |.|.|..|..|.:|.|.|.|.|..|.......|.:..:|..|
Zfish   410 RFTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSSP 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 10/38 (26%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353 9/22 (41%)
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 0/7 (0%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 25/84 (30%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 22/100 (22%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
zgc:152904NP_001070212.1 Ig 1..81 CDD:299845
IG_like 2..80 CDD:214653
IGc2 97..158 CDD:197706
Ig 177..273 CDD:299845 11/41 (27%)
I-set 184..270 CDD:254352 10/38 (26%)
Ig 272..369 CDD:299845 26/99 (26%)
I-set 274..367 CDD:254352 26/95 (27%)
IG_like 385..462 CDD:214653 19/84 (23%)
IGc2 386..454 CDD:197706 18/75 (24%)
FN3 468..561 CDD:238020 2/4 (50%)
fn3 <591..650 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
22.010

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