| Sequence 1: | NP_523713.2 | Gene: | Lac / 36363 | FlyBaseID: | FBgn0010238 | Length: | 359 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_996816.3 | Gene: | USH2A / 7399 | HGNCID: | 12601 | Length: | 5202 | Species: | Homo sapiens |
| Alignment Length: | 371 | Identity: | 78/371 - (21%) |
|---|---|---|---|
| Similarity: | 130/371 - (35%) | Gaps: | 138/371 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 19 FVQQTLAQRTPTISYITQEQIKDIGGTVEFDCSV-----------QYAKEYNVLFLKTDSDPVFL 72
Fly 73 STGSTLVIKDSRFSLRYDPNSS-TYKLQIKDIQETDAGT-----YTCQVVISTVHKVSAEVKLSV 131
Fly 132 RRP-----------------PVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPT 179
Fly 180 DSATYVGNTLRIKSVKKEDRGTYYCVADNGVS--------KGDRRNIN-----------VEVEFA 225
Fly 226 PVITVPRPRLGQALQYDMDLECHIEAYPPPA--------IVWTKDDIQLANNQHYSISHFATADE 282
Fly 283 YTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPP 328 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lac | NP_523713.2 | IG_like | 36..131 | CDD:214653 | 27/111 (24%) |
| FR1 | 37..50 | CDD:409353 | 4/12 (33%) | ||
| Ig strand A' | 37..42 | CDD:409353 | 1/4 (25%) | ||
| Ig strand B | 44..51 | CDD:409353 | 3/6 (50%) | ||
| CDR1 | 51..59 | CDD:409353 | 2/18 (11%) | ||
| Ig strand C | 59..63 | CDD:409353 | 2/3 (67%) | ||
| FR2 | 60..63 | CDD:409353 | 1/2 (50%) | ||
| CDR2 | 67..81 | CDD:409353 | 3/13 (23%) | ||
| Ig strand C' | 68..72 | CDD:409353 | 0/3 (0%) | ||
| Ig strand C' | 79..81 | CDD:409353 | 0/1 (0%) | ||
| FR3 | 84..115 | CDD:409353 | 11/36 (31%) | ||
| Ig strand D | 84..90 | CDD:409353 | 0/5 (0%) | ||
| Ig strand E | 94..102 | CDD:409353 | 4/8 (50%) | ||
| Ig strand F | 108..115 | CDD:409353 | 2/11 (18%) | ||
| CDR3 | 116..124 | CDD:409353 | 2/7 (29%) | ||
| FR4 | 124..130 | CDD:409353 | 0/5 (0%) | ||
| Ig strand G | 124..130 | CDD:409353 | 0/5 (0%) | ||
| Ig_3 | 134..208 | CDD:404760 | 14/90 (16%) | ||
| Ig strand B | 153..157 | CDD:409353 | 0/3 (0%) | ||
| Ig strand C | 166..170 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 187..191 | CDD:409353 | 0/3 (0%) | ||
| Ig strand F | 201..206 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 215..218 | CDD:409353 | 0/2 (0%) | ||
| Ig | 227..318 | CDD:416386 | 19/98 (19%) | ||
| Ig strand C | 256..260 | CDD:409353 | 2/11 (18%) | ||
| Ig strand E | 286..290 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 300..305 | CDD:409353 | 1/4 (25%) | ||
| USH2A | NP_996816.3 | LamGL | 146..283 | CDD:214722 | |
| Laminin_N | 291..516 | CDD:413488 | |||
| EGF_Lam | 517..565 | CDD:238012 | |||
| EGF_Lam | 574..639 | CDD:238012 | |||
| Laminin_EGF | 641..691 | CDD:395007 | |||
| EGF_Lam | 694..733 | CDD:214543 | |||
| Laminin_EGF | 747..795 | CDD:395007 | |||
| EGF_Lam | 794..844 | CDD:238012 | |||
| EGF_Lam | 847..897 | CDD:214543 | |||
| EGF_Lam | 900..948 | CDD:238012 | |||
| EGF_Lam | 950..1000 | CDD:238012 | |||
| EGF_Lam | 1001..>1037 | CDD:238012 | |||
| fn3 | 1058..1132 | CDD:394996 | |||
| fn3 | 1150..1227 | CDD:394996 | |||
| FN3 | 1242..1357 | CDD:238020 | |||
| FN3 | 1368..1451 | CDD:214495 | |||
| LamG | 1519..1678 | CDD:238058 | |||
| LamG | 1716..1868 | CDD:238058 | |||
| FN3 | 1956..2051 | CDD:238020 | |||
| FN3 | 2241..2313 | CDD:238020 | |||
| FN3 | 2329..2428 | CDD:238020 | |||
| FN3 | 2432..2528 | CDD:238020 | |||
| FN3 | 2533..2619 | CDD:238020 | |||
| FN3 | 2621..2719 | CDD:238020 | |||
| FN3 | 2724..2799 | CDD:238020 | |||
| FN3 | 2818..2920 | CDD:238020 | |||
| FN3 | 2925..3015 | CDD:238020 | |||
| FN3 | 3026..>3087 | CDD:238020 | |||
| FN3 | <3449..3494 | CDD:238020 | |||
| FN3 | 3503..3586 | CDD:238020 | |||
| FN3 | 3590..3676 | CDD:238020 | 1/3 (33%) | ||
| FN3 | 3680..3767 | CDD:238020 | 26/103 (25%) | ||
| fn3 | 3777..3856 | CDD:394996 | 17/103 (17%) | ||
| FN3 | 3866..3960 | CDD:238020 | 23/125 (18%) | ||
| FN3 | 3964..4057 | CDD:238020 | 2/2 (100%) | ||
| fn3 | 4161..4247 | CDD:394996 | |||
| FN3 | 4268..4351 | CDD:238020 | |||
| fn3 | 4357..4428 | CDD:394996 | |||
| FN3 | 4444..4516 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 4518..4541 | ||||
| FN3 | 4529..4627 | CDD:238020 | |||
| FN3 | 4636..4730 | CDD:238020 | |||
| FN3 | 4826..4927 | CDD:238020 | |||
| PDZ-binding | 5200..5202 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3510 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||