DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Kirrel3

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_006510620.1 Gene:Kirrel3 / 67703 MGIID:1914953 Length:803 Species:Mus musculus


Alignment Length:372 Identity:79/372 - (21%)
Similarity:135/372 - (36%) Gaps:111/372 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 ISNCVWSTLLLAIFVQQTLAQRT------PTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLK 64
            ::|.:.||.|          .||      |.::...|..:.|:|....|.|:........::::|
Mouse   316 VTNALGSTNL----------SRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMK 370

  Fly    65 TDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKL 129
                     .||.:|:.:.:            .|.:|.:::.|||.|.|:.|:..|.....||.|
Mouse   371 ---------RGSGVVLSNEK------------TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTL 414

  Fly   130 SVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTP-TITWRRENNAILPTDSATY--------- 184
            :|..||:||  |||:..|..|.:.|::|:....|.| .|.|..:.|.:....|..|         
Mouse   415 TVNGPPIIS--STQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVNTEE 477

  Fly   185 -VGNTLRIKSVKKEDRGTYY-CVADNGVSKGD------------RRNINVEVEFAPVITVPRPRL 235
             |.:||.|.::.:.|..|.| |.|.|......            :....:|.|..|:..:....:
Mouse   478 GVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAV 542

  Fly   236 GQALQYDMDLECHIEAY----------------------------PPPA----IVWTKDDIQLAN 268
            |..:.: :.|...|.|:                            |..|    :|..|:||:: .
Mouse   543 GAGVAF-LVLMATIVAFCCARSQRSTGGRPGISGRGTEKKARLRLPRRANLKGVVSAKNDIRV-E 605

  Fly   269 NQHYSISHFATADEYT--------------DSTLRVITVEKRQYGDY 301
            ..|...|....|:::|              ||.|:.:.|.|.:..::
Mouse   606 IVHKEPSSGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEF 652

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 21/94 (22%)
FR1 37..50 CDD:409353 3/12 (25%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 0/7 (0%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 1/1 (100%)
FR3 84..115 CDD:409353 7/30 (23%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 27/85 (32%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 3/5 (60%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 19/121 (16%)
Ig strand C 256..260 CDD:409353 2/7 (29%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 0/2 (0%)
Kirrel3XP_006510620.1 IG_like 54..143 CDD:214653
Ig strand A' 56..60 CDD:409353
Ig strand B 64..71 CDD:409353
Ig strand C 78..82 CDD:409353
Ig strand C' 84..87 CDD:409353
Ig strand D 97..101 CDD:409353
Ig strand E 104..116 CDD:409353
Ig strand G 132..143 CDD:409353
IgI_2_KIRREL3-like 149..246 CDD:409416
Ig strand B 166..170 CDD:409416
Ig strand C 180..184 CDD:409416
Ig strand E 210..214 CDD:409416
Ig strand F 224..229 CDD:409416
Ig strand G 239..242 CDD:409416
Ig <267..334 CDD:416386 6/27 (22%)
Ig strand B 267..274 CDD:409353
Ig strand C 279..286 CDD:409353
Ig strand C' 288..291 CDD:409353
Ig strand D 298..302 CDD:409353
Ig strand E 304..310 CDD:409353
Ig strand G 321..334 CDD:409353 5/22 (23%)
Ig 335..416 CDD:416386 22/101 (22%)
Ig strand A' 343..347 CDD:409353 0/3 (0%)
Ig strand B 350..360 CDD:409353 2/9 (22%)
Ig strand C 365..371 CDD:409353 1/14 (7%)
Ig strand E 381..387 CDD:409353 1/17 (6%)
IgI_5_KIRREL3 418..515 CDD:409479 28/98 (29%)
Ig strand B 436..440 CDD:409479 1/3 (33%)
Ig strand C 450..454 CDD:409479 1/3 (33%)
Ig strand E 481..485 CDD:409479 2/3 (67%)
Ig strand F 496..501 CDD:409479 2/4 (50%)
Ig strand G 509..512 CDD:409479 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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