DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and CG34353

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001287571.1 Gene:CG34353 / 5740590 FlyBaseID:FBgn0085382 Length:581 Species:Drosophila melanogaster


Alignment Length:293 Identity:87/293 - (29%)
Similarity:137/293 - (46%) Gaps:24/293 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 RTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDP 91
            |:.|..:||       |.|:...|.|.....|.|.:.:   ....|:.||..|..|.|..|    
  Fly    91 RSETFKFIT-------GETIVLPCEVANTDTYVVAWKR---GIAILTAGSVKVTPDPRVRL---- 141

  Fly    92 NSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQS-VVASEGSEVQM 155
             .:.:.|||:|...||||.|.||:......:::..|::.|  ||.|...||.. :...:||.|::
  Fly   142 -VNGFNLQIRDALPTDAGDYICQIATMDPREITHTVEILV--PPRIHHISTGGHLQVKKGSSVRI 203

  Fly   156 ECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINV 220
            ||.|:|.|.|.:||.|:|| |||........:.|.|::|.:...|.|.|.|:|.|.:.....:.:
  Fly   204 ECSATGNPMPNVTWSRKNN-ILPNGEEKLHSHVLSIENVDRHKGGVYICTANNRVGQPASSQVVL 267

  Fly   221 EVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTD 285
            .|.|:|.|:|.||.:.....::..|.|.:.....|.::|.||.:||...:.:.:.     ...:.
  Fly   268 HVLFSPEISVERPVVFSGEGHEATLVCIVHGETQPEVIWFKDTMQLDTTERHIME-----TRGSR 327

  Fly   286 STLRVITVEKRQYGDYVCKATNRFGEAEARVNL 318
            .||.:..|..:.:|:|.|.|.|:.|:|...:.|
  Fly   328 HTLIIRKVHPQDFGNYSCVAENQLGKARKTLQL 360

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 25/94 (27%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/13 (31%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 1/1 (100%)
FR3 84..115 CDD:409353 12/30 (40%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 0/7 (0%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 29/74 (39%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 22/90 (24%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
CG34353NP_001287571.1 IG_like 100..180 CDD:214653 25/87 (29%)
Ig 103..177 CDD:143165 22/81 (27%)
IG_like 191..269 CDD:214653 26/78 (33%)
IGc2 198..258 CDD:197706 25/60 (42%)
I-set 273..360 CDD:254352 23/91 (25%)
Ig 290..359 CDD:143165 18/73 (25%)
FN3 <466..524 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
32.810

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