DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and obscnb

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_021326058.1 Gene:obscnb / 572412 ZFINID:ZDB-GENE-070119-5 Length:6781 Species:Danio rerio


Alignment Length:315 Identity:76/315 - (24%)
Similarity:124/315 - (39%) Gaps:59/315 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 FVQQTLAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDS 83
            |:|:.|            .|:.|..|:|...|.           |.....||....|:.::....
Zfish  3383 FMQELL------------NQVGDEDGSVTLCCE-----------LSKPGVPVVWRKGTHVLHSGG 3424

  Fly    84 RFSLRYDPNSSTYKLQIKDIQETDAGTYTCQV--VISTVHKVSAEVKLSVRRPPVISDNSTQSVV 146
            :::::  ...:..:|:|.|::..|||.|.|..  .|:|     |.:|  |...||:.::..|:..
Zfish  3425 KYTIK--QVGTIVELKITDLKPEDAGEYACDCGDNITT-----ASIK--VNALPVVFNHELQNQE 3480

  Fly   147 ASEGSEVQMECYAS--GYPTPTITWRRENNAILPTDSATY----VGNT--LRIKSVKKEDRGTYY 203
            ..||..|.:.|..|  |.|   :.||:....|  .....|    ||..  |:|..||.||.|.|.
Zfish  3481 VQEGDSVTLHCELSKPGVP---VVWRKGTQEI--HSGGKYNIKQVGAAVELKIAGVKPEDAGNYA 3540

  Fly   204 CVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIE-AYPPPAIVWTKDDIQLA 267
            |...:.::     ..:::|...||: ..|....|.||....:..|.| :.|...:||.|...::.
Zfish  3541 CDCGDNIT-----TASIKVNALPVV-FSRELQNQVLQEGDSVTLHCELSKPGVPVVWRKGTQEIH 3599

  Fly   268 NNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETI 322
            :...|:|.....|.|     |::..|:....|||:|...:....|..:||....:
Zfish  3600 SGGKYNIKQDGAAVE-----LKITDVKPEDAGDYICDCGDNISSANIKVNALPVV 3649

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 21/96 (22%)
FR1 37..50 CDD:409353 4/12 (33%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 0/7 (0%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 2/3 (67%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 8/30 (27%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 25/81 (31%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/5 (20%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 23/91 (25%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 3/4 (75%)
obscnbXP_021326058.1 I-set 10..99 CDD:254352
I-set 110..199 CDD:254352
I-set 282..362 CDD:333254
I-set 369..452 CDD:333254
I-set 459..>523 CDD:333254
FN3 547..634 CDD:238020
Ig 762..809 CDD:319273
IG 836..901 CDD:214652
I-set 928..997 CDD:333254
I-set 1020..1089 CDD:333254
I-set 1112..1181 CDD:333254
I-set 1204..1273 CDD:333254
I-set 1296..1365 CDD:333254
Ig 1401..1469 CDD:319273
I-set 1483..1552 CDD:333254
Ig 1585..1644 CDD:319273
Ig 1689..1732 CDD:319273
I-set 1750..1833 CDD:333254
I-set 1840..1923 CDD:254352
I-set 1930..1999 CDD:333254
I-set 2018..2091 CDD:333254
I-set 2107..2190 CDD:333254
I-set 2196..2279 CDD:333254
I-set 2285..2368 CDD:333254
I-set 2374..2458 CDD:333254
I-set 2464..2547 CDD:333254
I-set 2553..>2620 CDD:333254
I-set 2643..2725 CDD:333254
I-set 2732..2815 CDD:333254
I-set 2820..2905 CDD:333254
I-set 2912..2995 CDD:333254
IG_like 3007..3084 CDD:214653
I-set 3090..3160 CDD:333254
I-set 3178..3260 CDD:333254
I-set 3266..3349 CDD:333254
IG_like 3389..>3452 CDD:214653 16/75 (21%)
I-set 3471..3541 CDD:333254 22/74 (30%)
I-set 3560..3630 CDD:333254 19/75 (25%)
I-set 3649..3719 CDD:333254 0/1 (0%)
I-set 3739..3808 CDD:333254
I-set 3828..3910 CDD:333254
IG 3926..4000 CDD:214652
I-set 4007..4090 CDD:254352
I-set 4095..>4162 CDD:333254
I-set 4186..4269 CDD:254352
I-set 4275..4358 CDD:333254
IG 4370..4449 CDD:214652
IG_like 4461..4538 CDD:214653
I-set 4636..>4700 CDD:333254
FN3 4725..4818 CDD:238020
I-set 4825..4906 CDD:333254
IQ 5065..5087 CDD:197470
I-set 5104..5177 CDD:254352
I-set 5331..5421 CDD:254352
I-set 5469..5559 CDD:254352
I-set 5583..5678 CDD:333254
SH3_Obscurin_like 5807..5869 CDD:212958
RhoGEF 5899..6075 CDD:321997
PH_Obscurin 6084..6208 CDD:270059
I-set 6216..6308 CDD:254352
I-set 6310..6399 CDD:333254
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.