DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and igsf9bb

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_009293693.1 Gene:igsf9bb / 569554 ZFINID:ZDB-GENE-091112-15 Length:1439 Species:Danio rerio


Alignment Length:359 Identity:92/359 - (25%)
Similarity:138/359 - (38%) Gaps:76/359 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VW--STLLLAIF-VQQTLAQRTPTISYITQEQIKDIGGTVEFDCSV-------QYAKEY------ 58
            :|  :||:.::| .:.|.||....:....|......|.||...|.|       .|..|:      
Zfish     2 IWYVATLIASVFSTRGTAAQGAHGVREEPQFVTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVP 66

  Fly    59 -----NVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVI- 117
                 |..|.....||.:....| |..|.|              |:|:.::..|.|.|.|:|:: 
Zfish    67 IPFFINFRFYPPHVDPEYAGRAS-LHGKSS--------------LRIERVRSEDQGWYECKVLML 116

  Fly   118 ----STVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILP 178
                .|.|. .:.|.|:|..||..:|...|.|.|.||..:.:.|.|.|.|.|:::|.||.|.:  
Zfish   117 EQQYHTFHN-GSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPV-- 178

  Fly   179 TDSATY--VGNTLRIKSVKKEDRGTYYCVA--DNGVSKGDRRNINVEVEFAPVITVPRPRLGQAL 239
            .||..|  ...:|.:.|:.:||||.|.|.|  :.|.:....|.:   |:..|.|..|...:...:
Zfish   179 QDSTKYKVSDGSLTLVSISREDRGAYTCRAYSEQGEAVHTTRLL---VQGPPFIVSPPENITVNI 240

  Fly   240 QYDMDLECHIEAYPPPAI---VWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDY 301
            ..|....|..||||....   .|.:|::...|:....:|..      .|.:|.:..|:....|.|
Zfish   241 SQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSIL------IDGSLIISQVKPEDAGKY 299

  Fly   302 VCKATNRFGEAEARVNLFETIIPVCPPACGQAYI 335
            .|..:|..|.               ||: ..||:
Zfish   300 TCSPSNSLGR---------------PPS-ASAYL 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 27/117 (23%)
FR1 37..50 CDD:409353 3/12 (25%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 3/25 (12%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 4/13 (31%)
Ig strand C' 68..72 CDD:409353 2/3 (67%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/30 (20%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/12 (17%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 29/77 (38%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 20/93 (22%)
Ig strand C 256..260 CDD:409353 0/6 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
igsf9bbXP_009293693.1 IG_like 30..113 CDD:214653 22/97 (23%)
Ig 41..113 CDD:143165 19/86 (22%)
IG_like 144..223 CDD:214653 28/83 (34%)
IGc2 151..208 CDD:197706 22/58 (38%)
I-set 227..319 CDD:254352 25/113 (22%)
Ig <263..319 CDD:299845 16/77 (21%)
Ig_2 326..414 CDD:290606
IG_like 329..403 CDD:214653
IG_like 424..504 CDD:214653
Ig 440..504 CDD:299845
FN3 509..604 CDD:238020
FN3 620..704 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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