Protein Alignment Lac and dscama

DIOPT Version :9

• Sequence 1: NP_523713.2
• Gene: Lac / 36363
• FlyBaseID: FBgn0010238
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: XP_021334866.1
• Gene: dscama / 568643
• ZFINID: ZDB-GENE-050310-7
• Length: 2025
• Species: Danio rerio
• Alignment Length: 261
• Identity: 73/261 - (27%)
• Similarity: 110/261 - (42%)
• Gaps: 51/261 - (19%)

  Fly    82 DSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEV--KLSVRRP--PVISDNST 142
            ||||      ..|...|.|:..|.:|.|:|.|:|..|   ..:|||  :|:|:.|  .|:   |.
Zfish   269 DSRF------RQSVTGLLIERAQPSDTGSYVCEVWNS---YGNAEVIGRLTVKEPLKAVV---SP 321

  Fly   143 QSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKE---------- 197
            :.|..|.||:|.:.|..:|.....::|.|..:.|       ..|..:|:..:.||
Zfish   322 RKVKGSVGSQVSLSCSVTGSDEFELSWYRNGDKI-------NTGANIRMNGINKENLVMDGMAKS 379

  Fly   198 DRGTYYCVADNGVSKGDRRNINVEVEFAPVITVP-RPRLGQALQYD-------MDLECHIEAYPP 254
            |.|.|.|.:        |:......:|..||... .|::..|....       :.|.||::..|.
Zfish   380 DGGVYQCFS--------RKAKMSAQDFVQVILEDGTPKILSAFSEKVVGPNDFVSLTCHVKGTPQ 436

  Fly   255 PAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEA--EARVN 317
            |||.||.||..:|.:..:.|.|..||:....|.|.:..::.|..|.|.|...|..|..  :||:|
Zfish   437 PAITWTLDDEVVAKDSRHRIVHSITAEGNVVSYLNISHIQVRDSGVYRCTCNNSAGTVSYQARIN 501

  Fly   318 L 318
            :
Zfish   502 V 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lac	NP_523713.2	IG_like	36..131	CDD:214653	18/50 (36%)
		FR1	37..50	CDD:409353
		Ig strand A'	37..42	CDD:409353
		Ig strand B	44..51	CDD:409353
		CDR1	51..59	CDD:409353
		Ig strand C	59..63	CDD:409353
		FR2	60..63	CDD:409353
		CDR2	67..81	CDD:409353
		Ig strand C'	68..72	CDD:409353
		Ig strand C'	79..81	CDD:409353
		FR3	84..115	CDD:409353	10/30 (33%)
		Ig strand D	84..90	CDD:409353	2/5 (40%)
		Ig strand E	94..102	CDD:409353	3/7 (43%)
		Ig strand F	108..115	CDD:409353	3/6 (50%)
		CDR3	116..124	CDD:409353	1/7 (14%)
		FR4	124..130	CDD:409353	3/7 (43%)
		Ig strand G	124..130	CDD:409353	3/7 (43%)
		Ig_3	134..208	CDD:404760	21/85 (25%)
		Ig strand B	153..157	CDD:409353	1/3 (33%)
		Ig strand C	166..170	CDD:409353	0/3 (0%)
		Ig strand E	187..191	CDD:409353	0/3 (0%)
		Ig strand F	201..206	CDD:409353	2/4 (50%)
		Ig strand G	215..218	CDD:409353	1/2 (50%)
		Ig	227..318	CDD:416386	30/100 (30%)
		Ig strand C	256..260	CDD:409353	2/3 (67%)
		Ig strand E	286..290	CDD:409353	2/3 (67%)
		Ig strand F	300..305	CDD:409353	2/4 (50%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352	18/50 (36%)
		IG_like	321..402	CDD:214653	20/95 (21%)
		I-set	408..502	CDD:333254	28/93 (30%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810