DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and igsf9ba

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_009289969.2 Gene:igsf9ba / 567389 ZFINID:ZDB-GENE-060503-729 Length:1475 Species:Danio rerio


Alignment Length:334 Identity:87/334 - (26%)
Similarity:130/334 - (38%) Gaps:58/334 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VW--STLLLAIF-VQQTLAQRTPTISYITQEQIKDIGGTVEFDCSVQ---------YAKEY---- 58
            :|  :||:.::| .:.|.||....:....|......|.:|...|.|.         |..|:    
Zfish     2 IWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFG 66

  Fly    59 -------NVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVV 116
                   |..|.....||.:.          .|.||.     ....|||:.::..|.|.|.|:|:
Zfish    67 VPIPFFINFRFYPPHVDPEYA----------GRASLH-----GKASLQIEQVRSEDQGWYECRVL 116

  Fly   117 I-----STVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAI 176
            :     .|.|. .:.|.|:|..||..||...|.|.|.||..:.:.|.|.|.|.|.:||.||.:.:
Zfish   117 MLEQQYDTFHN-GSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQL 180

  Fly   177 LPTDSATYVGNTLRIKSVKKEDRGTYYCVA--DNGVSKGDRRNINVEVEFAPVITVPRPRLGQAL 239
            ..|...|....:|.::::.:||||.|.|.|  |.|.:....|.:   |:..|.|..|...:...:
Zfish   181 TSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLL---VQGPPYIVTPPENITVNI 242

  Fly   240 QYDMDLECHIEAYPPPAI---VWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDY 301
            ..:....|..||||....   .|.:|::...|:....:..|      .|.||.:..|:....|.|
Zfish   243 SQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIF------IDGTLIIYRVKPEDAGKY 301

  Fly   302 VCKATNRFG 310
            .|..:|..|
Zfish   302 TCSPSNSLG 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 26/119 (22%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 3/27 (11%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 2/3 (67%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/30 (33%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/12 (17%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 28/75 (37%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 20/87 (23%)
Ig strand C 256..260 CDD:409353 0/6 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
igsf9baXP_009289969.2 IG 30..115 CDD:214652 21/99 (21%)
I-set 139..225 CDD:254352 30/88 (34%)
I-set 229..321 CDD:333254 21/88 (24%)
Ig 345..415 CDD:325142
Ig 438..503 CDD:319273
FN3 511..606 CDD:238020
FN3 622..706 CDD:238020
Atrophin-1 <924..1361 CDD:331285
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.