DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and paplna

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_005169942.1 Gene:paplna / 562930 ZFINID:ZDB-GENE-070815-4 Length:1187 Species:Danio rerio


Alignment Length:303 Identity:66/303 - (21%)
Similarity:98/303 - (32%) Gaps:103/303 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 SVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDP-----NSSTYKLQ----------- 99
            ||..:.:.|....:.||...:.|..|      |||::.|.|     ...|.|||           
Zfish   919 SVSGSSQNNAGISEVDSSQSYTSQSS------SRFNIDYSPLVEARAGQTAKLQCSVLPVSAIHA 977

  Fly   100 --------------------------IKDIQETDAGTYTCQVVIS---TVHKVSAEV--KLSVRR 133
                                      ||.:...|:|.|||.|..:   ...:|...|  .|.:.:
Zfish   978 VTIHWSRAGQPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITK 1042

  Fly   134 PPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVG--NTLRIKSVKK 196
            .|:..|     ||  :||..|:.|..:| ....:.|.|....:.|.....:|.  .||.:.:|:.
Zfish  1043 APIDVD-----VV--QGSTAQLACVVTG-ENVNVGWSRNGVPVRPDGHRVHVSADGTLILNNVQS 1099

  Fly   197 EDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMD---------------LE 246
            .|.|||.|.|..|         .:.|..|..|     ||.:..|.|:|               ..
Zfish  1100 VDEGTYTCNAYTG---------TLSVSAAAEI-----RLAKTPQQDIDGGQFSSSDCVDQPELAN 1150

  Fly   247 CHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLR 289
            |.:..|           .:|.::.:||....::...|....||
Zfish  1151 CKLIVY-----------ARLCSSPYYSSFCCSSCARYATDRLR 1182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 27/126 (21%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 66/303 (22%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 15/72 (21%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 5/44 (11%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 0/10 (0%)
FR4 124..130 CDD:409353 1/7 (14%)
Ig strand G 124..130 CDD:409353 1/7 (14%)
Ig_3 134..208 CDD:404760 22/75 (29%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 3/4 (75%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 14/78 (18%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/4 (50%)
Ig strand F 300..305 CDD:409353
paplnaXP_005169942.1 TSP1 24..75 CDD:214559
ADAM_spacer1 181..293 CDD:310520
TSP1 303..356 CDD:214559
TSP1 388..442 CDD:214559
TSP1 449..498 CDD:214559
TSP1 504..557 CDD:214559
KU 720..771 CDD:238057
Ig_3 839..906 CDD:316449
IGc2 960..1022 CDD:197706 12/61 (20%)
I-set 1039..1121 CDD:333254 25/98 (26%)
PLAC 1142..1173 CDD:312271 5/41 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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