DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and si:dkey-182g1.4

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_005161711.1 Gene:si:dkey-182g1.4 / 560083 ZFINID:ZDB-GENE-060503-808 Length:370 Species:Danio rerio


Alignment Length:417 Identity:77/417 - (18%)
Similarity:136/417 - (32%) Gaps:170/417 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 SNCVWSTLLLAIFVQQTLAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPV- 70
            |.|:|.:      |..|             |::|.|.           .:|.:.|.|.||.|.| 
Zfish    16 SMCLWHS------VDMT-------------EEVKIIS-----------VREGDPLALHTDVDEVS 50

  Fly    71 --------FLSTGSTLVIKDSRFSLRYDPNSSTYK----------LQIKDIQETDAGTYTCQVV- 116
                    |.:|....|.:.|:.:..||....|::          |.|.:.:.||:|.|...:. 
Zfish    51 RYLLIQWMFENTRIAEVNRLSKINSTYDGPEETFRGRLKLDQTGSLTITNTRSTDSGLYKLSIYK 115

  Fly   117 ---ISTVH-------------KVSAEVKLS-----------VRRPPVISDNSTQSVVASEGSEVQ 154
               ||.:|             .||::...|           :.:.|..:....:::...||..|.
Zfish   116 LQQISYIHFQVTIYGRSSGSDCVSSKCTKSNSVTNQPDETDITKLPQSTSAEVKTISVMEGDSVT 180

  Fly   155 MECYASGYPT-PTITWRRENNAI-----LPTDSATYVGNTLRIKS-VKKEDRGTYYCV----ADN 208
            :....:.... ..|.|..||..|     |..:.|.|.|...|.:. :|.::.|:...:    .|:
Zfish   181 LHTGVTDVQKYLLIQWMLENTRIAEVNRLAQNRAAYDGPHGRFRDRLKLDETGSLIIINTTTTDS 245

  Fly   209 GVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQ--- 270
            |:.|               :|:.   :.:::..:.:|..::.:.|..::      |.|.|||   
Zfish   246 GLYK---------------LTLV---IQESIYVNFNLTVYVSSSPEKSL------ISLMNNQTED 286

  Fly   271 -HYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETII--PVCPPACGQ 332
             :.:..|..::|.:                 |.|             .|.||:|  .:|      
Zfish   287 ANITDLHQTSSDSF-----------------YCC-------------GLPETVIRLVIC------ 315

  Fly   333 AYIAGAEDVSATSFALVG--ILAALLF 357
                          ||||  :||.|::
Zfish   316 --------------ALVGVVVLALLVY 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 29/141 (21%)
FR1 37..50 CDD:409353 3/12 (25%)
Ig strand A' 37..42 CDD:409353 2/4 (50%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 5/22 (23%)
Ig strand C' 68..72 CDD:409353 2/12 (17%)
Ig strand C' 79..81 CDD:409353 1/1 (100%)
FR3 84..115 CDD:409353 9/40 (23%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 3/17 (18%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 3/24 (13%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 16/84 (19%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 0/8 (0%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 12/94 (13%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
si:dkey-182g1.4XP_005161711.1 Ig 55..126 CDD:299845 16/70 (23%)
Ig 176..268 CDD:299845 19/109 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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