DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and hepacam2

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001232014.1 Gene:hepacam2 / 558612 ZFINID:ZDB-GENE-060503-135 Length:457 Species:Danio rerio


Alignment Length:276 Identity:67/276 - (24%)
Similarity:105/276 - (38%) Gaps:74/276 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 PVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQV---------VISTVHKVS 124
            |...|:...|::|:  .:::..|:.|   |:..::.|...|.|..||         .:|....|:
Zfish    77 PSTTSSIPNLLVKN--ITMQELPDVS---LRFVNLDEDTKGEYELQVNIVFDENAPPVSVTKTVT 136

  Fly   125 AEVKLSVRRPPVIS-----------DNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILP 178
            ..|.:.| ..||||           ||.|.:..|..|:|::.:            |.::|..:.|
Zfish   137 VTVSVPV-STPVISKTPESELVEDRDNVTLTCSALHGTEIRYK------------WLKDNMLVSP 188

  Fly   179 TDSATYV--GNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAP--------------- 226
            :|..|:.  ..||.|..|:|||.|.|.|.|.|.:|....:..::.|.:.|               
Zfish   189 SDRHTFSEDNGTLFINPVRKEDMGQYICEAHNQISSEQSQQTDLSVFYGPYNLAVNCDQALKTEG 253

  Fly   227 VITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVI 291
            |.||....|.       ..||:.::.||...:|    |....|        .|....|...|.|.
Zfish   254 VFTVNPGELA-------FFECNADSNPPNTFLW----ISKTGN--------GTEIVMTGPRLEVK 299

  Fly   292 TVEKRQYGDYVCKATN 307
            |.|..|..:::|:|.|
Zfish   300 TYELPQGKEFLCRAFN 315

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 15/70 (21%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353 3/11 (27%)
Ig strand C' 68..72 CDD:409353 1/2 (50%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/30 (20%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 26/86 (30%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 21/81 (26%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 1/4 (25%)
hepacam2NP_001232014.1 IG_like 152..234 CDD:214653 24/93 (26%)
Ig 157..234 CDD:299845 24/88 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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