DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and sdk1a

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_009297968.1 Gene:sdk1a / 558391 ZFINID:ZDB-GENE-081104-374 Length:2245 Species:Danio rerio


Alignment Length:282 Identity:64/282 - (22%)
Similarity:108/282 - (38%) Gaps:41/282 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 SSTYKLQIKDIQETDAGTYTCQVVI--STVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQM 155
            |.:.:|.|.:...||.|.|.|:.::  |:|....|...||:...|..:....:.::......|.:
Zfish   372 SFSRRLTIINPTSTDVGMYVCEALLLDSSVKPAEARAFLSI
TEAPYFTAEPRRKMMGEVEKSVDI 436

  Fly   156 ECYASGYPTPTITWRRENNAILPTDSATY-----VGNTLRIKSVKKEDRGTYYCVADNGVSKGDR 215
            :|.|.|.|.|.:.|.::...:...::..|     :|  |:::.::..|.|.:.|.|.|...:...
Zfish   437 QCQARGVPMPKLEWYKDAVPLSKLNNPRYKIISSMG--LQVRKLQPSDAGIFQCFARNSAGEAQV 499

  Fly   216 RNINVEVEFAPVITVPRPRLGQALQYDMDL----------ECHIEAYPPPAIVWTKDDIQLANNQ 270
            .........||..|.|          .:|:          .|.:...|.|||||.:|...||:..
Zfish   500 HTYLDV
TSMAPAFTAP----------PLDITVTDGAVAAFTCRVSGAPKPAIVWRRDTQILASGS 554

  Fly   271 HYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETI---IPVCPPACGQ 332
             ..|..|...:   ...|::..|..:..|:|.|.|.|..|...|..:|  |:   ..:..|...:
Zfish   555 -VQIPRFTLLE---SGGLQIQPVVLQDTGNYTCYAANSEGAINASASL--TVWSRTSISSPPTDR 613

  Fly   333 AYIAGAE---DVSATSFALVGI 351
            ..|.|..   :..||....||:
Zfish   614 RVIKGTTAILECGATHDPRVGV 635

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 12/39 (31%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353 8/21 (38%)
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/9 (22%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 15/78 (19%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 24/100 (24%)
Ig strand C 256..260 CDD:409353 3/3 (100%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
sdk1aXP_009297968.1 I-set 125..208 CDD:254352
Ig 125..204 CDD:299845
IG_like 222..302 CDD:214653
Ig 236..287 CDD:299845
Ig_3 322..394 CDD:290638 8/21 (38%)
I-set 323..412 CDD:254352 12/39 (31%)
I-set 416..505 CDD:254352 16/90 (18%)
Ig 436..500 CDD:299845 14/65 (22%)
I-set 510..600 CDD:254352 26/105 (25%)
Ig 527..600 CDD:299845 22/78 (28%)
I-set 605..693 CDD:254352 7/31 (23%)
Ig 610..693 CDD:299845 6/26 (23%)
FN3 697..788 CDD:238020
fn3 800..886 CDD:278470
FN3 901..997 CDD:238020
FN3 1002..1090 CDD:238020
FN3 1100..1196 CDD:238020
FN3 1206..1301 CDD:238020
FN3 1308..1397 CDD:238020
FN3 1408..1501 CDD:238020
FN3 1507..1602 CDD:238020
FN3 1616..1722 CDD:238020
FN3 1732..1825 CDD:238020
FN3 1830..1919 CDD:238020
FN3 1931..2021 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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