DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and igsf9a

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_005155702.1 Gene:igsf9a / 557459 ZFINID:ZDB-GENE-060503-288 Length:1619 Species:Danio rerio


Alignment Length:287 Identity:74/287 - (25%)
Similarity:121/287 - (42%) Gaps:38/287 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 AKEYNVLFLKTDSD-PVFLSTGSTLVIKDSRFSLRYDPNSSTY---KLQIKDIQETDAGTYTCQV 115
            |.:|.:.:::...| |:|:..|     ...|....||...|.:   .||:..:|..|.|.|.|::
Zfish    52 ASQYVIEWVRQGFDTPIFMQLG-----VHPRVHPDYDGRVSLFGGTSLQMSGLQLEDEGWYECRI 111

  Fly   116 --VISTVHKVSAE---VKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNA 175
              :..|..:..:.   .:|||..|||:::.|...|....|..:.::|.|.|.|.|||||.::...
Zfish   112 LPLDQTTEEAGSSGSWTRLSVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDGAP 176

  Fly   176 ILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNI-NVEVEFAPVITVPRPRLGQAL 239
            |.|......|..::...:|.:|..|.|.|...|  |:|:..:: .:::...|||.:|.......:
Zfish   177 IKPQHKVKMVNGSVSFHAVSREAAGQYQCYTSN--SEGNATHVTRLKIIGPPVIIIPPSDTVLNM 239

  Fly   240 QYDMDLECHIEAYPP-PAIVWTKDDIQLANNQHYSISHFATADE-YTDSTLRVITVEKRQYGDYV 302
            ..|..|:|..||.|| ...||.:..:.:     |.|....:..: ..|.||.:..:.....|:|.
Zfish   240 SQDAKLKCQAEADPPNMTYVWQRQGVDI-----YHIDSLKSRIKVIVDGTLLISRLAPEDSGNYT 299

  Fly   303 CKATNRFGEAEARVNLFETIIPVCPPA 329
            |..||.              :||.|.|
Zfish   300 CMPTNG--------------LPVSPSA 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 19/84 (23%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353 1/3 (33%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 4/14 (29%)
Ig strand C' 68..72 CDD:409353 2/4 (50%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 11/33 (33%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 3/10 (30%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 0/8 (0%)
Ig strand G 124..130 CDD:409353 0/8 (0%)
Ig_3 134..208 CDD:404760 23/73 (32%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 3/3 (100%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 22/92 (24%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
igsf9aXP_005155702.1 IG_like 27..110 CDD:214653 16/62 (26%)
Ig 35..111 CDD:299845 17/63 (27%)
I-set 140..221 CDD:254352 23/82 (28%)
IGc2 151..212 CDD:197706 20/62 (32%)
Ig 233..318 CDD:299845 23/99 (23%)
I-set 233..318 CDD:254352 23/99 (23%)
Ig <349..402 CDD:299845
IG_like 423..502 CDD:214653
Ig 435..498 CDD:143165
FN3 507..602 CDD:238020
fn3 614..696 CDD:278470
PHA02666 1105..>1312 CDD:222914
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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