DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and zgc:198329

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001091716.1 Gene:zgc:198329 / 557409 ZFINID:ZDB-GENE-080226-6 Length:414 Species:Danio rerio


Alignment Length:374 Identity:76/374 - (20%)
Similarity:148/374 - (39%) Gaps:88/374 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 WSTLLLAIFVQQTLAQ--RTPTISYITQEQIKDIGGTVEF-------DCSVQYAKEYNVLFL--- 63
            |:..::|.| :|.|.|  :.|.::.      ..:||:|:|       ....|:..::..:.:   
Zfish     9 WTLWMVACF-EQCLGQDLQFPELNN------GAVGGSVKFTPNNPPSTAINQFTWQFETILILTG 66

  Fly    64 KTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVK 128
            |.||..|           .|.:..|...:.:|..|::.::...|:|:|...|  :||:......:
Zfish    67 KPDSPTV-----------SSEYQDRVFLDKNTLALELWNLTFRDSGSYNLSV--NTVNGDEIREQ 118

  Fly   129 LSVRRPPVISD---NSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYV----- 185
            .|::...:|||   ...|..:..:.|...:....||..| ::.|.::|:   |..|::.:     
Zfish   119 TSLQVYEIISDVTLTGPQETLIEDESSANITSKGSGNIT-SVQWMKDNS---PLSSSSRIIFSSD 179

  Fly   186 GNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAP-VITVPRPRLGQALQYDMDLECHI 249
            ..::.|..|::.|.|...|...|.||....::..: :.:.| .:::..|.:.. |...:.|.|..
Zfish   180 NRSVYISPVERSDTGELQCTYSNPVSSETAKHTLI-INYGPDGVSIEGPNVVD-LGVQIFLSCSA 242

  Fly   250 EAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQY---GDYVCKATNRF-- 309
            .:.|..:..||      .|.....:    |.|:|        |::|..:   |:|:|.|.||.  
Zfish   243 NSEPSASFSWT------FNGSDTGV----TTDKY--------TIDKTDFNNSGEYICTAFNRVTN 289

  Fly   310 -GEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFA--LVGILAAL 355
             .|.:....|.:               ||...:|..:.|  ::|:|.|:
Zfish   290 RRELKTHALLVQ---------------AGGGGLSGGAIAGIVIGVLVAV 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 19/104 (18%)
FR1 37..50 CDD:409353 4/19 (21%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 3/13 (23%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/30 (20%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 17/81 (21%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 20/96 (21%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
zgc:198329NP_001091716.1 Ig 33..124 CDD:299845 20/103 (19%)
I-set 132..215 CDD:254352 17/87 (20%)
Ig 140..216 CDD:299845 16/80 (20%)
Ig_2 229..288 CDD:290606 18/77 (23%)
IG_like 229..285 CDD:214653 16/74 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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