DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and kirrel3l

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001092814.2 Gene:kirrel3l / 557315 ZFINID:ZDB-GENE-070831-1 Length:755 Species:Danio rerio


Alignment Length:311 Identity:80/311 - (25%)
Similarity:128/311 - (41%) Gaps:57/311 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 QRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVI--KDSRFSLR 88
            |..|:::...|.|....|..|.|.||.....|...........|:..:.|.:|.:  ..|.|:  
Zfish   217 QHPPSVTLSVQPQTVMEGAKVLFICSASANPEITGYRWSKGGVPISEANGDSLEVTADHSYFT-- 279

  Fly    89 YDPNSSTYKLQIKDIQETDAGTYTCQVV-------ISTVHKVSAEVKLSVRRPPVISDNSTQSVV 146
             ||.|                   |:|.       :||:..|....:|.....|.|.|       
Zfish   280 -DPVS-------------------CEVSNSVGSTNVSTLVDVQFGPRLLTEPKPQIVD------- 317

  Fly   147 ASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYC---VADN 208
              .|.:....|..:|.|..|:.|.::.:.::.::|     |||::|:|.::|.|||.|   |...
Zfish   318 --IGMDAAFTCSWTGNPPLTLAWTKQGSNVVLSNS-----NTLQLKAVTQDDTGTYTCKAIVPRI 375

  Fly   209 GVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDM-DLECHIEAYPPP-AIVWTKDDIQLANNQ- 270
            ||::   |::.:.|...|:||....:  ||:::.. .|||.:.:.||| .||||..|:.|::.. 
Zfish   376 GVAE---RDVTLTVNGPPIITAEATQ--QAIKHSKGKLECLVGSSPPPDKIVWTFGDMMLSSGSS 435

  Fly   271 -HYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFE 320
             .:|:....:......|.:...|:.:.....|.|.|.||||...|.|.|.|
Zfish   436 GRFSVQTVNSDQGVLSSLILSETLAQDFQLRYNCTAWNRFGTGTALVTLEE 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 22/103 (21%)
FR1 37..50 CDD:409353 4/12 (33%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 3/15 (20%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/3 (0%)
FR3 84..115 CDD:409353 5/30 (17%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 0/7 (0%)
Ig strand F 108..115 CDD:409353 1/6 (17%)
CDR3 116..124 CDD:409353 2/14 (14%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 21/76 (28%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 3/3 (100%)
Ig strand F 201..206 CDD:409353 3/7 (43%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 28/94 (30%)
Ig strand C 256..260 CDD:409353 2/3 (67%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
kirrel3lNP_001092814.2 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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