DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and iglon5

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001017775.2 Gene:iglon5 / 550472 ZFINID:ZDB-GENE-050417-297 Length:332 Species:Danio rerio


Alignment Length:284 Identity:81/284 - (28%)
Similarity:126/284 - (44%) Gaps:32/284 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 GGTVEFDCSVQ-------YAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQI 100
            |.:|...|.:.       :....|:||..||...:           |||.||. :.|:|.:.::|
Zfish    41 GESVVLRCKIDEEVTHKAWLNRSNILFTGTDKWSL-----------DSRVSLE-NNNNSDFSIRI 93

  Fly   101 KDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTP 165
            :.:...|.|.|||........: :|.|.|.|:.|..|. |.:|....:||.:|.:.|.|.|.|.|
Zfish    94 ERVMVADEGPYTCSFQARNKPR-TAHVYLIV
QVPARIV-NISQDKSVNEGEDVNLFCLAVGRPEP 156

  Fly   166 TITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITV 230
            ||||:.....:|..      |..|.|..:|:.....:.|:.:|||:..|.|.:.|.|.:.|:||.
Zfish   157 TITWKDFKYGLLNE------GEFLEITEIKRHQAEDFECITNNGVAPPDTRKVKVTV
NYPPIITD 215

  Fly   231 PRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEK 295
            .:....|..:..: |.|...|.|..:..|.:||.:...    |.:.....:|.|.|.|....|.:
Zfish   216 VKNMPAQVGKTAI-LRCEAMAVPTASFEWYRDDRRPVE----SDNTLKIKNEKTRSLLLFTNVTE 275

  Fly   296 RQYGDYVCKATNRFGEAEARVNLF 319
            :.:|:|.|.|:||.|.:.|.:.||
Zfish   276 KHFGNYTCFASNRLGASNASMLLF 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 24/94 (26%)
FR1 37..50 CDD:409353 2/6 (33%)
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 0/14 (0%)
Ig strand C 59..63 CDD:409353 2/3 (67%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 0/13 (0%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 11/30 (37%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 0/7 (0%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 22/73 (30%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 3/3 (100%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 24/90 (27%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
iglon5NP_001017775.2 IG_like 33..123 CDD:214653 24/94 (26%)
Ig 35..123 CDD:299845 24/94 (26%)
Ig 125..>183 CDD:299845 21/64 (33%)
I-set 128..207 CDD:254352 27/85 (32%)
IG_like 217..298 CDD:214653 22/85 (26%)
ig 223..296 CDD:278476 21/77 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170576307
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8424
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
65.850

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