DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and opcml

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:320 Identity:80/320 - (25%)
Similarity:124/320 - (38%) Gaps:55/320 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 SYITQEQIKDIGGTVEFDCS-------VQYAKEYNVLFL---KTDSDP--VFLSTGSTLVIKDSR 84
            ||:........|.:....||       |.:.....:||.   |...||  |.|:|.         
Zfish    36 SYLKDNITVRQGDSAVLKCSMDNKVSRVAWLNRTTILFTGNEKWSLDPRVVLLNTA--------- 91

  Fly    85 FSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASE 149
                    .:.|.::|.::...|.|.|.|. :::.....|.:|.|.|:.|..|.:.|| .|..:|
Zfish    92 --------VNEYSIKILNVNLYDEGPYVCS-ILTNKKPESTKVHLIVQVPARIVNVST-DVSVNE 146

  Fly   150 GSEVQMECYASGYPTPTITWR---RENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVS 211
            ||.|.:.|.|.|.|.|:|.|:   .:.|.|:..      |..:.:..:.|:..|:|.|:..|.:|
Zfish   147 GSNVSLMCLAIGRPEPSILWKFRSSKGNRIVTE------GEYVEMTGITKDMSGSYDCITSNDIS 205

  Fly   212 KGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISH 276
            ..|.|.:.|.|.:.|||:..| ..|.|:.....|.|...|.|.....|.|.:.::.|    ..:.
Zfish   206 PPDVRTVQVTVNYPPVISRAR-STGTAVGQKGVLWCEASAVPLADFQWFKGERRILN----GFNG 265

  Fly   277 FATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLF----------ETIIPVC 326
            ....::...|.|....|.:..||:|.|.|.|..|...|.:.|:          ..:.|.|
Zfish   266 VKIENKGKQSMLTFFNVSEEDYGNYTCVAINTLGITNASIILYGPGAIHDVNNAALSPTC 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 21/106 (20%)
FR1 37..50 CDD:409353 1/12 (8%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 2/14 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 5/15 (33%)
Ig strand C' 68..72 CDD:409353 3/5 (60%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/30 (20%)
Ig strand D 84..90 CDD:409353 0/5 (0%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 0/7 (0%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 23/76 (30%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 23/90 (26%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
opcmlNP_001005580.1 Ig 41..129 CDD:299845 21/105 (20%)
IG_like 41..129 CDD:214653 21/105 (20%)
IG_like 139..216 CDD:214653 26/83 (31%)
IGc2 146..202 CDD:197706 18/61 (30%)
I-set 219..307 CDD:254352 24/92 (26%)
ig 223..307 CDD:278476 21/88 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170576309
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8424
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
76.750

Return to query results.
Submit another query.