Protein Alignment Lac and LSAMP

DIOPT Version :10

• Sequence 1: NP_523713.2
• Gene: Lac / 36363
• FlyBaseID: FBgn0010238
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_001305844.1
• Gene: LSAMP / 4045
• HGNCID: 6705
• Length: 361
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 93/307 - (30%)
• Similarity: 138/307 - (44%)
• Gaps: 46/307 - (14%)

  Fly    34 ITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDP------- 91
            ||..|    |.|....|.|:          ..:|...:|:....:.....::||  ||
Human    41 ITVRQ----GDTAILRCVVE----------DKNSKVAWLNRSGIIFAGHDKWSL--DPRVELEKR 89

  Fly    92 NSSTYKLQIKDIQETDAGTYTCQVVISTVHK-VSAEVKLSVRRPPVISDNSTQSVVASEGSEVQM 155
            :|..|.|:|:.:...|.|:|||.|  .|.|: .:::|.|.|:.||.|| |.:..|..:|||.|.:
Human    90 HSLEYSLRIQKVDVYDEGSYTCSV--QTQHEPKTSQVYLIVQVPPKIS-NISSDVTVNEGSNVTL 151

  Fly   156 ECYASGYPTPTITWRRENNAILPTDSATYVGNT--LRIKSVKKEDRGTYYCVADNGVSKGDRRNI 218
            .|.|:|.|.|.||||.    :.|| ...:.|..  |.|..:.:|..|.|.|.|.|.||..|.:.:
Human   152 VCMANGRPEPVITWRH----LTPT-GREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQV 211

  Fly   219 NVEVEFAPVITVPRPR---LGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATA 280
            .|.|.:.|.||..:..   .|:    ...|:|...|.|.|...|.:||.::  |....:...:|.
Human   212 KVTVNYPPTITESKSNEATTGR----QASLKCEASAVPAPDFEWYRDDTRI--NSANGLEIKSTE 270

  Fly   281 DEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCP 327
            .:   |:|.|..|.:..||:|.|.|.|:.|...|.:.||:.::|..|
Human   271 GQ---SSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLPTIP 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lac	NP_523713.2	IG_like	36..131	CDD:214653	25/102 (25%)
		Ig strand B	46..50	CDD:409381	0/3 (0%)
		Ig strand C	60..63	CDD:409381	0/2 (0%)
		Ig strand E	96..100	CDD:409381	2/3 (67%)
		Ig strand F	110..115	CDD:409381	3/4 (75%)
		Ig strand G	124..127	CDD:409381	0/2 (0%)
		Ig_3	134..208	CDD:464046	29/75 (39%)
		Ig	227..318	CDD:472250	25/93 (27%)
		Ig strand C	256..260	CDD:409353	0/3 (0%)
		Ig strand E	286..290	CDD:409353	2/3 (67%)
		Ig strand F	300..305	CDD:409353	2/4 (50%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:472250	27/104 (26%)
		Ig strand B	49..53	CDD:409353	0/3 (0%)
		Ig strand C	61..65	CDD:409353	0/3 (0%)
		Ig strand E	94..98	CDD:409353	2/3 (67%)
		Ig strand F	108..113	CDD:409353	3/4 (75%)
		Ig strand G	121..124	CDD:409353	0/2 (0%)
		Ig_3	131..201	CDD:464046	29/75 (39%)
		Ig_3	218..294	CDD:464046	23/84 (27%)