DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr10

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_729591.1 Gene:dpr10 / 39180 FlyBaseID:FBgn0052057 Length:408 Species:Drosophila melanogaster


Alignment Length:337 Identity:68/337 - (20%)
Similarity:103/337 - (30%) Gaps:104/337 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 IGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQET 106
            :|.:....|.|::.....|.::: ..|...|:.|:.....|.||...|..:...:.||||..|:.
  Fly    67 VGKSAYLGCRVKHLGNKTVAWIR-HRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQR 130

  Fly   107 DAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRR 171
            |||.|.||:....|...|..:.:             ..::.:|.|::..:.|             
  Fly   131 DAGVYECQISTQP
VRSYSVNLNI-------------VDLIDAETSDIMQQYY------------- 169

  Fly   172 ENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRL- 235
                   .|.|.|:......:|...|..|.                      |.|:.||..|.. 
  Fly   170 -------NDDAFYIAENRVYQSSNDEFAGM----------------------FGPIQTVAVPTAT 205

  Fly   236 ---GQALQYD----MDLECHIE--AYPPPAIVWTKDDIQLANNQHYSISHFAT-ADEYTDSTLRV 290
               |..|..|    ::|.|.|:  ..||..|.|...|..|:.........|.| ..|.|.|.|.:
  Fly   206 ILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLI 270

  Fly   291 ITVEKRQYGDYVCKATN-----------------------------------RFGEAEARVNLFE 320
            ...:....|.|.|..:|                                   .||:|...|.:..
  Fly   271 YDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQAVRVIS 335

  Fly   321 TIIP--VCPPAC 330
            |::.  |...||
  Fly   336 TMVAALVLLEAC 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 24/88 (27%)
FR1 37..50 CDD:409353 1/7 (14%)
Ig strand A' 37..42 CDD:409353 68/337 (20%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/30 (43%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 9/73 (12%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 0/4 (0%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 29/136 (21%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
dpr10NP_729591.1 Ig 63..143 CDD:299845 22/76 (29%)
IG_like 210..297 CDD:214653 21/86 (24%)
IGc2 217..287 CDD:197706 18/69 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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