back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lac and robo1

DIOPT Version :9

Sequence 1:	NP_523713.2	Gene:	Lac / 36363	FlyBaseID:	FBgn0010238	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_476899.1	Gene:	robo1 / 37603	FlyBaseID:	FBgn0005631	Length:	1395	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	85/302 - (28%)
Similarity:	127/302 - (42%)	Gaps:	43/302 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LAQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSD-PVFLSTGSTLVIKDSRFSL 87
            :.|..|......::|:...|.|..|.|||.......||:.|.:.: ||            ||..:
  Fly   250 IVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPV------------SRARI 302

  Fly    88 RYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSE 152
            .:|..|    |:|.:|..||.|||.|: ..:.|.::||...|.|..||..:...:...|...| .
  Fly   303 LHDEKS----LEISNITPTDEGTYVCE-AHNNVGQISARASLIVHAPPNFTKRPSNKKVGLNG-V 361

  Fly   153 VQMECYASGYPTPTITWRRENNAILPTDSATY------VGNTLRIKSVKKEDRGTYYCVADNGVS 211
            ||:.|.|||.|.|::.|.:|..:.|...::::      ...||:|..|::||.|.|.|.|.:.|
  Fly   362 VQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQEDEGYYVCSAFSVV- 425

  Fly   212 KGDRRNINVEVEFAPVITVPRP--RLGQALQ-----YDMDLECHIEAYPPPAIVWTKDDIQLANN 269
              |...:.|.::.:.:...|.|  ::|.|.|     ....|.|.....|.|.|.|..|...:...
  Fly   426 --DSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAG 488

  Fly   270 QHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGE 311
            ..|||        ...|:|||..::....|.|.|.|:...||
  Fly   489 NRYSI--------IQGSSLRVDDLQLSDSGTYTCTASGERGE 522

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.