DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Strn-Mlck

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001261019.1 Gene:Strn-Mlck / 36753 FlyBaseID:FBgn0265045 Length:8255 Species:Drosophila melanogaster


Alignment Length:345 Identity:87/345 - (25%)
Similarity:133/345 - (38%) Gaps:97/345 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 IGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQET 106
            :|.:....|:::.|....|.:.|   |.:.||:.|      .|..:|  ...||..|.|..:.|.
  Fly  6335 LGSSFTLQCNMRGAPRPQVTWFK---DGIQLSSSS------ERVKIR--QIGSTCALTIATVSEL 6388

  Fly   107 DAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSV------------VASEGSE------- 152
            |:|.|||:.. ::..:||...:|.     |:||:.....            ||..|..       
  Fly  6389 DSGRYTCEAT-NSKGRVSTFARLQ-----V
VSDSRIYEADSRLKEIAHGRNVADVGDSLPIFTMR 6447

  Fly   153 -----------VQMECYASGYPTPTITWRRENNAILPTD-----SATYVGNTLRIKSVKKEDRGT 201
                       |::.|...|||.|.|.|.:::. ::.||     ||.....||.|.:...:|.||
  Fly  6448 LRDRRVQVTYPVRLTCQIVGYPVPEILWYKDDE-LIHTDRKHLISAEGQFFTLEIAATTLDDSGT 6511

  Fly   202 YYCVADNG-----------VSKGDRRNINVEVEFAPVITVPRP-----RLGQALQYDMDLECHIE 250
            |.|:|.|.           |.||.|..|      :|...||..     |.|..::    |...:|
  Fly  6512 YTCLARNELGSVSCHCTLVV
DKGIRAYI------SPDFYVPLDPFYIFREGSEIR----LSTKVE 6566

  Fly   251 AYPPPAIVWTKDDIQLANNQHYSISHFATADE--YTDSTLRVITVEKRQYGDYVCKATNRFGEAE 313
            |||...:.|.::.::|..::..:    ||.|.  |.:..:...||  |..|.|||.|:|..|:.|
  Fly  6567 AYPSVGVTWHRNGMRLRPSRRLT----ATLDSNGYVELIIAEATV--RDAGIYVCVASNVVGKVE 6625

  Fly   314 ARVNLFETIIPVCPPACGQA 333
            .          :|..|..:|
  Fly  6626 T----------ICRVAVEEA 6635

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 24/88 (27%)
FR1 37..50 CDD:409353 1/7 (14%)
Ig strand A' 37..42 CDD:409353 87/345 (25%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/13 (31%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 12/30 (40%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 4/7 (57%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 0/7 (0%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 27/108 (25%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 3/4 (75%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 26/97 (27%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 3/4 (75%)
Strn-MlckNP_001261019.1 IG_like 51..127 CDD:214653
Ig <69..>112 CDD:299845
I-set 137..226 CDD:254352
I-set 235..314 CDD:254352
Ig_2 244..314 CDD:290606
I-set 438..513 CDD:254352
Ig 454..510 CDD:143165
I-set 537..626 CDD:254352
Ig 555..618 CDD:299845
I-set 636..713 CDD:254352
Ig 652..712 CDD:143165
SMC_N <2190..2854 CDD:280601
I-set 5300..5388 CDD:254352
IGc2 5313..5378 CDD:197706
IG 5412..5482 CDD:214652
IGc2 5413..5481 CDD:197706
I-set 5542..5627 CDD:254352
Ig 5556..5621 CDD:143165
Ig 5654..5721 CDD:143165
I-set 5784..5874 CDD:254352
IGc2 5797..5864 CDD:197706
I-set 5887..5970 CDD:254352
Ig 5902..5966 CDD:143165
I-set 5997..6086 CDD:254352
Ig 6026..6083 CDD:143165
I-set 6097..6187 CDD:254352
Ig 6114..6187 CDD:299845
FN3 6216..6310 CDD:238020
I-set 6321..6412 CDD:254352 24/93 (26%)
Ig 6328..6412 CDD:299845 24/93 (26%)
I-set 6442..6531 CDD:254352 22/89 (25%)
Ig 6459..6528 CDD:143165 22/69 (32%)
I-set 6541..6632 CDD:254352 28/110 (25%)
IGc2 6555..6622 CDD:197706 21/76 (28%)
I-set 6662..6754 CDD:254352
Ig 6679..6751 CDD:143165
I-set 6779..6868 CDD:254352
IGc2 6793..6858 CDD:197706
Ig 6938..7022 CDD:299845
I-set 6939..7028 CDD:254352
IG 7075..7140 CDD:214652
Ig 7075..7140 CDD:143165
IG 7167..7239 CDD:214652
Ig 7173..7239 CDD:143165
Ig 7392..7475 CDD:299845
IG 7406..7475 CDD:214652
FN3 7489..7588 CDD:238020
S_TKc 7620..7876 CDD:214567
STKc_MLCK 7626..7876 CDD:271005
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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