DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr19

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001260336.1 Gene:dpr19 / 34408 FlyBaseID:FBgn0032233 Length:385 Species:Drosophila melanogaster


Alignment Length:325 Identity:64/325 - (19%)
Similarity:111/325 - (34%) Gaps:76/325 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 GGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETD 107
            ||.....|.|:......|.:::. .|...|:.|.:....|.||.:.:..:...:.|:||.::|.|
  Fly    55 GGLAILPCVVKVNSPATVSWIRR-KDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREED 118

  Fly   108 AGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMEC-YASGYPTPTITWRR 171
            .|.|.||:.|.....:..|:|:.   ..|...:|...:...|.|.:::|| .......|...:..
  Fly   119 RGFYECQLS
IYPTQSIVIELKIV---EAVAEISSAPELHIDETSTLRLECKLKRATENPAFVFWY 180

  Fly   172 ENNAILPTDS-----ATYVGNT------LRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFA 225
            .::.::..||     .|.:|.:      ....|...:.|.|....:.|||       :|..:..:
  Fly   181 HDSKMINYDSQGGFVVTSIGQSNPQSGQFYRSSPANKSRATMPMESSNGV-------LNSLLGSS 238

  Fly   226 PVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRV 290
            ..|..|...:..:..|                         ...||.|.       ...:.::.|
  Fly   239 DAIKAPAANVPSSTPY-------------------------MTQQHQSA-------YLLNPSVSV 271

  Fly   291 ITVEK---RQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGIL 352
            :||::   |..|:|.|..:|      ||            ||....::...|..:|...|...||
  Fly   272 LTVKQVNFRHAGNYTCAPSN------AR------------PASITVHVLRGEKTAAMQHANRSIL 318

  Fly   353  352
              Fly   319  318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 23/87 (26%)
FR1 37..50 CDD:409353 2/6 (33%)
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/30 (33%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 14/85 (16%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 0/9 (0%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 16/93 (17%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
dpr19NP_001260336.1 IG_like 50..127 CDD:214653 20/72 (28%)
IGc2 55..125 CDD:197706 18/70 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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