DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr2

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001014480.4 Gene:dpr2 / 3346227 FlyBaseID:FBgn0261871 Length:410 Species:Drosophila melanogaster


Alignment Length:317 Identity:70/317 - (22%)
Similarity:108/317 - (34%) Gaps:93/317 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 GGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETD 107
            |.|...:|.|....:.:|.::: ..|...|:.|......|.||.:....:|..:.|.:|..|..|
  Fly   121 GHTAAINCRVDNLGDKSVSWIR-KRDLHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRD 184

  Fly   108 AGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRE 172
            :|.|.|||  :|..|:|...:|:|    :::....::::|.                        
  Fly   185 SGIYECQV--NTEPKISMAFRLNV
----IVTPPDAKAIIAG------------------------ 219

  Fly   173 NNAILPTDSATYVGN----TLRIK--SVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVP 231
                 |||....||:    |..:|  :...:|.|..|...                  .|.|..|
  Fly   220 -----PTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYWYR------------------GPYILTP 261

  Fly   232 RPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKR 296
                             ..|:|..|.:    |:|       .||..:|..|...|.||:...:..
  Fly   262 -----------------FVAHPNDAAI----DLQ-------RISMESTLAEKLQSRLRIANAQLL 298

  Fly   297 QYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGILA 353
            ..|:|.|..|.    ||| .::...:|....||..|...|.....|..|..||.:||
  Fly   299 DTGNYTCMPTT----AEA-ASVVVNVINDESPAAMQKSRAIRTSGSMRSSRLVLLLA 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 25/87 (29%)
FR1 37..50 CDD:409353 2/6 (33%)
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/30 (33%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 11/79 (14%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/7 (14%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 21/90 (23%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
dpr2NP_001014480.4 IG_like 113..206 CDD:214653 25/87 (29%)
Ig 116..192 CDD:299845 19/71 (27%)
ig 220..306 CDD:278476 27/131 (21%)
IG_like 220..306 CDD:214653 27/131 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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