DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr3

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001014459.2 Gene:dpr3 / 3346208 FlyBaseID:FBgn0053516 Length:522 Species:Drosophila melanogaster


Alignment Length:338 Identity:65/338 - (19%)
Similarity:104/338 - (30%) Gaps:103/338 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 AQRTPTISYITQEQIKDIGGTVE--FDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSL 87
            :|..|...:.....|....|..|  ..|.|....:.:|.::: ..|...|:.|:.....|.||.:
  Fly   232 SQSLPIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIR-KRDLHILTVGTATYTSDKRFQV 295

  Fly    88 RYDPNSSTYKLQIKDIQETDAGTYTCQVVIS---------TVHKVSAEVKLSVRRPPVISDNSTQ 143
            ....:|..:.|.:|.....|:|.|.|||...         .:.::|.:.|..:..||.:...:  
  Fly   296 TESKDSREWTLHVKAPLAKDSGIYECQVNTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKA-- 358

  Fly   144 SVVASEGSEVQMECYASGYPTPT------ITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTY 202
                  ||.:.:.|...   .|:      |.|.|..:.|.|.|                      
  Fly   359 ------GSAIILNCLVQ---QPSVKDIGPIYWYRGEHMITPFD---------------------- 392

  Fly   203 YCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLA 267
               ||:|               .|.|...|....|.:..|..          |..:.::.|:|: 
  Fly   393 ---ADDG---------------QPEIPAGRGEHPQGIPEDTS----------PNDIMSEVDLQM- 428

  Fly   268 NNQHYSISHFAT-------ADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIP- 324
                    .|||       ..:...|.||:...:....|:|.|:.|.. ..|...|::.....| 
  Fly   429 --------EFATRIAMESQLGDTLKSRLRISNAQTTDTGNYTCQPTTA-SSASVLVHVINDENPA 484

  Fly   325 ------VCPPACG 331
                  .||.|.|
  Fly   485 AMQKSGACPCALG 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 23/105 (22%)
FR1 37..50 CDD:409353 3/14 (21%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 2/8 (25%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 9/30 (30%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 0/16 (0%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 13/79 (16%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/9 (11%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 0/4 (0%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 19/97 (20%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
dpr3NP_001014459.2 Ig 243..330 CDD:299845 21/87 (24%)
IG_like 243..329 CDD:214653 21/86 (24%)
Ig 350..464 CDD:299845 31/183 (17%)
IG_like <441..477 CDD:214653 9/36 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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