DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr4

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001014616.2 Gene:dpr4 / 3346160 FlyBaseID:FBgn0053512 Length:323 Species:Drosophila melanogaster


Alignment Length:202 Identity:51/202 - (25%)
Similarity:77/202 - (38%) Gaps:28/202 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 QEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQI 100
            :|....:|......|.|:...:..|.::: ..|...|:.|......|.||...:...|..:.|:|
  Fly    53 REVTATVGQAALLHCRVRNLGDRAVSWIR-KRDLHILTVGILTYTNDQRFQSLHSEGSDEWTLRI 116

  Fly   101 KDIQETDAGTYTCQVVISTVHKVSAEVKLS--VRRPPVISDNSTQSVVASEGSEVQMECYASGYP 163
            ...|..|:|||.|||  ||..|:|...:|:  |.|..::.:   ..:....||::.:.|.|...|
  Fly   117 SSPQPRDSGTYECQV--STEPKISQGFRLNVVVSRAKILGN---AELFIKSGSDINLTCLAMQSP 176

  Fly   164 TPT--ITW-----------RRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDR 215
            .|.  |.|           |...|.|....:.|   :.|.|......|.|.|.|    ..|..|.
  Fly   177 VPPSFIYWYKGKRVMNYSQRGGINVITERSTRT---SKLLIAKATPADSGNYTC----SPSSSDS 234

  Fly   216 RNINVEV 222
            .::.|.|
  Fly   235 ASVVVHV 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 27/96 (28%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 11/30 (37%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 3/7 (43%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 18/86 (21%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 2/16 (13%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386
Ig strand C 256..260 CDD:409353
Ig strand E 286..290 CDD:409353
Ig strand F 300..305 CDD:409353
dpr4NP_001014616.2 V-set 53..146 CDD:284989 27/95 (28%)
IG_like 53..145 CDD:214653 27/94 (29%)
ig 153..227 CDD:278476 17/79 (22%)
IG_like 161..>227 CDD:214653 17/68 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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