DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Dscaml1

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001101611.1 Gene:Dscaml1 / 315615 RGDID:1304887 Length:2111 Species:Rattus norvegicus


Alignment Length:307 Identity:83/307 - (27%)
Similarity:126/307 - (41%) Gaps:39/307 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 AQRTPTISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRY 89
            |:..|||......|....|..||..|:   |..|.:..::      :|..|..|. .|||::.|.
  Rat   280 AESIPTILDGFHSQEVWTGHAVELPCA---ASGYPIPAIR------WLKDGRPLP-ADSRWAKRI 334

  Fly    90 DPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQ 154
            .      .|.|.|::..|:|||.|:|. :|.....|...|:|..|..:: .:.:.:....||.|.
  Rat   335 T------GLTISDLRTEDSGTYICEVT-NTFGSAEANGVLTVIDPLHVT-LTPKKLKTGIGSTVI 391

  Fly   155 MECYASGYPTPTITWRRENNAILPTDSATYVG---NTLRIKSVKKEDRGTYYCVADNGVSKGDRR 216
            :.|..:|.|..||.|.|....:||.::.:..|   .||.|.|.:|...|.|.|.|        .|
  Rat   392 LSCALTGSPEFTIRWYRNTELVLPGEAISIRGLSNETLLISSAQKSHSGAYQCFA--------TR 448

  Fly   217 NINVEVEFAPVITVP-RPRLGQALQ-------YDMDLECHIEAYPPPAIVWTKDDIQLANNQHYS 273
            ......:||.::... .||:..:..       ....|.|..:..|||.:.|..||..:..:..:.
  Rat   449 KAQTAQDFAIIVLEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRDGSHR 513

  Fly   274 ISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAE--ARVNL 318
            .:.:..:|..|.|.:.|...:.|..|.|.|.|.|..|.||  ||:|:
  Rat   514 TNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINV 560

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 26/94 (28%)
FR1 37..50 CDD:409353 4/12 (33%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 2/6 (33%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/30 (33%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 23/76 (30%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 25/100 (25%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Dscaml1NP_001101611.1 IG 101..173 CDD:214652
IGc2 101..168 CDD:197706
Ig 183..276 CDD:299845
IG_like 195..276 CDD:214653
I-set 291..369 CDD:254352 26/94 (28%)
IGc2 298..359 CDD:197706 23/77 (30%)
IGc2 386..447 CDD:197706 22/68 (32%)
I-set 466..560 CDD:254352 25/93 (27%)
Ig 466..556 CDD:299845 23/89 (26%)
IGc2 577..635 CDD:197706
IG_like 665..744 CDD:214653
Ig 673..739 CDD:143165
I-set 748..843 CDD:254352
Ig7_DSCAM 765..843 CDD:143211
I-set 849..942 CDD:254352
Ig 861..949 CDD:299845
FN3 945..1039 CDD:238020
FN3 1046..1143 CDD:238020
fn3 1151..1237 CDD:278470
FN3 1249..1340 CDD:238020
IGc2 1364..1428 CDD:197706
FN3 1442..1532 CDD:238020
FN3 1546..1618 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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