DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and sdk

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001284756.1 Gene:sdk / 31017 FlyBaseID:FBgn0021764 Length:2265 Species:Drosophila melanogaster


Alignment Length:387 Identity:95/387 - (24%)
Similarity:140/387 - (36%) Gaps:97/387 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 PTISYITQEQIKDIG-GTVEFDC--SVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYD 90
            |.|....|:....:| |.||..|  :.:...|...|:||   |.:.:.|...      |.:|. |
  Fly   261 PEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLK---DGLAVETAGV------RHTLN-D 315

  Fly    91 PNSSTYKLQIKDIQETDAGTYTCQVVIST--VHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEV 153
            |.:.|  |.:.....:.:|.|||||.:.:  ...|||..:|.:..||:.............|.:|
  Fly   316 PWNRT--LALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQV 378

  Fly   154 QMECYASGYPTPTITWRRENNAI-LPTDSATY---VGNTLRIKSVKKEDRGTYYCVADN------ 208
            |:.|...|.|||.:.|.|...:: ...:|..|   ..|||.||.:..:|...:.|:|.|      
  Fly   379 QLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENS 443

  Fly   209 ----------------------------------GVSKG------DRRNINVEVEF--APVITVP 231
                                              |..||      |||.   |..|  ||::.:|
  Fly   444 ASTWLRVKTKTAKNRVKRLAQPRILRVRASHAGLGSEKGSESGSSDRRK---EFRFASAPIMELP 505

  Fly   232 RPRLGQALQ-YDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEK 295
             |:...||. .|..:.|.....|.|.|.|..::.||.:     ||......|..|  |.:..:..
  Fly   506 -PQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVD-----ISSRVQILESGD--LLISNIRS 562

  Fly   296 RQYGDYVCKATNRFG--EAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGILAAL 355
            ...|.|:|...|..|  :.||.:::......:.||            |..|  .|:|:.|.|
  Fly   563 VDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPP------------VDTT--VLLGLTATL 610

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 28/99 (28%)
FR1 37..50 CDD:409353 4/13 (31%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 4/8 (50%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/30 (33%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 0/9 (0%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 22/77 (29%)
Ig strand B 153..157 CDD:409353 2/3 (67%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 3/3 (100%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 2/2 (100%)
Ig 227..318 CDD:416386 24/93 (26%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
sdkNP_001284756.1 Ig 71..157 CDD:299845
I-set 72..150 CDD:254352
Ig 172..245 CDD:299845
IG_like 280..356 CDD:214653 24/87 (28%)
Ig 280..343 CDD:299845 20/74 (27%)
IG_like 375..450 CDD:214653 21/74 (28%)
Ig 378..447 CDD:143165 20/68 (29%)
Ig 506..587 CDD:299845 23/87 (26%)
IG_like 506..587 CDD:214653 23/87 (26%)
I-set 592..682 CDD:254352 8/33 (24%)
Ig 595..682 CDD:299845 8/30 (27%)
FN3 686..789 CDD:238020
FN3 798..893 CDD:238020
FN3 901..1005 CDD:238020
fn3 1011..1094 CDD:278470
FN3 1108..1202 CDD:238020
FN3 1210..1308 CDD:238020
fn3 1317..1402 CDD:278470
FN3 1415..1507 CDD:238020
FN3 1513..1608 CDD:238020
fn3 1617..1708 CDD:278470
FN3 1722..1823 CDD:238020
FN3 1828..1920 CDD:238020
FN3 1927..2016 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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