DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Igsf9

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001100667.1 Gene:Igsf9 / 304982 RGDID:1304566 Length:1179 Species:Rattus norvegicus


Alignment Length:353 Identity:82/353 - (23%)
Similarity:131/353 - (37%) Gaps:59/353 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 CVWSTLLLAIFVQQTLAQRTPTISYITQEQIKDIGGTVEFDCS------------VQYAKEYNVL 61
            |:..|:|..|..|....:|.|.:..:    :...|.:....|.            :::.: :..|
  Rat     4 CLRLTILSLILSQGADGRRKPEVVSV----VGRAGESAVLGCDLLPPAGRPPLHVIEWLR-FGFL 63

  Fly    62 FLKTDSDPVFLSTGSTLVIKDSRFSLRYDPN-------SSTYKLQIKDIQETDAGTYTCQVVIST 119
            .      |:|:..|        .:|.|.||:       .:...|||:.::..|.|.|.|:|:...
  Rat    64 L------PIFIQFG--------LYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLD 114

  Fly   120 VHKVSAE------VKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILP 178
            .|....:      |.|:|..||...:.....:...|...|.:.|.|.|.|.|.:||:.....:..
  Rat   115 QHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQDLGK 179

  Fly   179 TDSATYVGN-TLRIKSVKKEDRGTYYCVADNGVSKGD-RRNINVEVEFAPVITVPRPRLGQALQY 241
            ......|.| ||.|:.|::...|.|.|.|.:  ::|. .....:.|...|||.||..........
  Rat   180 GQGQVQVRNGTLWIRRVERGSAGDYTCQASS--TEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQ 242

  Fly   242 DMDLECHIEAYPPP-AIVWTKDDIQLANNQHYSISHFATADE-YTDSTLRVITVEKRQYGDYVCK 304
            |:.|.|..||||.. ...|.:|.|.:     :.||...:... ..|.:|.:...:....|.|.|.
  Rat   243 DVSLACRAEAYPANLTYSWFQDRINV-----FHISRLQSRVRILVDGSLWLQATQPDDAGHYTCV 302

  Fly   305 ATNRF---GEAEARVN-LFETIIPVCPP 328
            .:|.|   ..|.|.:. |:...:.|.||
  Rat   303 PSNGFPHPPSASAYLTVLYPAQVTVMPP 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 21/119 (18%)
FR1 37..50 CDD:409353 1/12 (8%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 0/19 (0%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 11/37 (30%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/11 (9%)
Ig strand G 124..130 CDD:409353 1/11 (9%)
Ig_3 134..208 CDD:404760 21/74 (28%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 3/4 (75%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 25/96 (26%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Igsf9NP_001100667.1 IG 28..110 CDD:214652 17/100 (17%)
Ig strand A 136..139 CDD:409353 1/2 (50%)
IG_like 143..223 CDD:214653 20/81 (25%)
Ig strand A' 145..148 CDD:409353 0/2 (0%)
Ig strand B 154..161 CDD:409353 2/6 (33%)
Ig strand C 167..172 CDD:409353 2/4 (50%)
Ig strand C' 175..177 CDD:409353 0/1 (0%)
Ig strand D 183..187 CDD:409353 0/3 (0%)
Ig strand E 189..193 CDD:409353 2/3 (67%)
Ig strand F 202..210 CDD:409353 4/7 (57%)
Ig strand G 213..223 CDD:409353 1/9 (11%)
Ig_3 226..305 CDD:404760 22/83 (27%)
putative Ig strand A 226..230 CDD:409353 2/3 (67%)
putative Ig strand A' 235..239 CDD:409353 0/3 (0%)
putative Ig strand B 241..251 CDD:409353 3/9 (33%)
putative Ig strand C' 267..270 CDD:409353 0/7 (0%)
putative Ig strand D 279..282 CDD:409353 0/2 (0%)
putative Ig strand E 284..290 CDD:409353 1/5 (20%)
putative Ig strand F 297..305 CDD:409353 3/7 (43%)
putative Ig strand G 310..319 CDD:409353 2/8 (25%)
Ig 322..407 CDD:416386 3/9 (33%)
Ig strand A' 324..328 CDD:409353 0/3 (0%)
Ig strand B 333..347 CDD:409353
Ig strand C 353..359 CDD:409353
Ig strand C' 362..364 CDD:409353
Ig strand D 371..374 CDD:409353
Ig strand E 378..382 CDD:409353
Ig strand F 391..399 CDD:409353
Ig 418..503 CDD:416386
Ig strand A 418..421 CDD:409353
Ig strand A' 427..430 CDD:409353
Ig strand B 436..443 CDD:409353
Ig strand C 449..454 CDD:409353
Ig strand C' 457..459 CDD:409353
Ig strand D 462..466 CDD:409353
Ig strand E 469..473 CDD:409353
Ig strand F 482..490 CDD:409353
Ig strand G 493..503 CDD:409353
FN3 508..599 CDD:238020
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 766..807
PHA03247 <777..1062 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..846
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..895
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..979
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding. /evidence=ECO:0000250 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.000

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