DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr7

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001096850.2 Gene:dpr7 / 2768865 FlyBaseID:FBgn0053481 Length:312 Species:Drosophila melanogaster


Alignment Length:228 Identity:49/228 - (21%)
Similarity:90/228 - (39%) Gaps:63/228 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 ISYITQE------QIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRY 89
            :|.:..|      ::|:.|..     :|.:.::.::..|.|:   ::..||      |.|||:.:
  Fly    61 VSAVVDEIAILRCRVKNKGNR-----TVSWMRKRDLHILTTN---IYTYTG------DQRFSVIH 111

  Fly    90 DPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQ----------- 143
            .|.|..:.|:|...|..|:|.|.|||  :|..|::..:.|.     ||:||..|           
  Fly   112 PPGSEDWDLKIDYAQPRDSGVYECQV--NTEPKINLAICLQ-----VIADNDFQDLKTKKRFYDT 169

  Fly   144 -----------SVVASEGSEVQMECYASGYPTPTITWRRENNAI----------LPTDSATYVGN 187
                       .:.....|.:.:.|..:.: .|::.|...::.:          |.|:. |.||.
  Fly   170 KSARAKILGSTEIHVKRDSTIALACSVNIH-APSVIWYHGSSVVDFDSLRGGISLETEK-TDVGT 232

  Fly   188 TLRIKSVKK--EDRGTYYCVADNGVSKGDRRNI 218
            |.|:...:.  .|.|.|.||.:..:....|.::
  Fly   233 TSRLMLTRASLRDSGNYTCVPNGAIPASVRVHV 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 26/100 (26%)
FR1 37..50 CDD:409353 3/18 (17%)
Ig strand A' 37..42 CDD:409353 2/10 (20%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 12/30 (40%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 21/107 (20%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386
Ig strand C 256..260 CDD:409353
Ig strand E 286..290 CDD:409353
Ig strand F 300..305 CDD:409353
dpr7NP_001096850.2 V-set 56..145 CDD:284989 26/99 (26%)
IG_like 58..140 CDD:214653 24/94 (26%)
IG_like 179..265 CDD:214653 17/87 (20%)
Ig 187..257 CDD:299845 16/71 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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