DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dpr1

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001286645.1 Gene:dpr1 / 2768858 FlyBaseID:FBgn0040726 Length:367 Species:Drosophila melanogaster


Alignment Length:238 Identity:56/238 - (23%)
Similarity:88/238 - (36%) Gaps:54/238 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 WSTLLLAIFVQ---QTLAQRTPTISYIT---------------QEQIKDIGGTVEFDCSVQYAKE 57
            |..||..:.::   ..||...||.|..|               :.....:|.|....|.|:...:
  Fly    18 WLLLLSMVLLRGYNAALAPTPPTTSTTTISPSNLLPYFDFDVPRNLTVTVGQTGFLHCRVERLGD 82

  Fly    58 YNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHK 122
            .:|.::: ..|...|:.|.|....|.||.:.....|:.:.||||..|..|:|.|.||  |:|..|
  Fly    83 KDVSWIR-KRDLHILTAGGTTYTSDQRFQVLRPDGSANWTLQIKYPQPRDSGVYECQ--INTEPK 144

  Fly   123 VS-------AEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYP--TPTITWRRENNAI-- 176
            :|       .|:|..:..|   ||     ::...||::.:.|.....|  ...|.|.:.:..:  
  Fly   145 MSLSYTFNVVELKAEIFGP---SD-----LMVKTGSDINLTCKIMQGPHELGNIFWYKGSEMLDG 201

  Fly   177 --------------LPTDSATYVGNTLRIKSVKKEDRGTYYCV 205
                          :..|....:.:.|:||.....|.|.|.||
  Fly   202 KGENEIDSSMARIRVEDDWTDGLTSRLKIKRAMPGDTGNYTCV 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 29/101 (29%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/13 (31%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 12/30 (40%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 3/7 (43%)
FR4 124..130 CDD:409353 3/12 (25%)
Ig strand G 124..130 CDD:409353 3/12 (25%)
Ig_3 134..208 CDD:404760 18/90 (20%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 3/5 (60%)
Ig strand G 215..218 CDD:409353
Ig 227..318 CDD:416386
Ig strand C 256..260 CDD:409353
Ig strand E 286..290 CDD:409353
Ig strand F 300..305 CDD:409353
dpr1NP_001286645.1 Ig 59..154 CDD:299845 27/97 (28%)
IG_like 60..150 CDD:214653 27/92 (29%)
IG_like 163..257 CDD:214653 18/90 (20%)
Ig 174..244 CDD:143165 11/69 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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