| Sequence 1: | NP_523713.2 | Gene: | Lac / 36363 | FlyBaseID: | FBgn0010238 | Length: | 359 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055200.1 | Gene: | SIGLEC7 / 27036 | HGNCID: | 10876 | Length: | 467 | Species: | Homo sapiens |
| Alignment Length: | 377 | Identity: | 79/377 - (20%) |
|---|---|---|---|
| Similarity: | 134/377 - (35%) | Gaps: | 89/377 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 32 SYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPV---FLSTGSTLVIK------------ 81
Fly 82 ----DSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTV------HKVSAEVKLSVRRPPV 136
Fly 137 ISDNSTQSVVASEGSEVQMECYA-----SGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKK 196
Fly 197 EDRGTYYC-VADNGVSKGDRRNINVEVEFAP---VITVPRPR----------------LGQALQY 241
Fly 242 DMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKAT 306
Fly 307 NRFGEAEARVNL------FETIIPVCPPACGQAYIAGAEDVSATSFALVGIL 352 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lac | NP_523713.2 | IG_like | 36..131 | CDD:214653 | 27/119 (23%) |
| FR1 | 37..50 | CDD:409353 | 2/12 (17%) | ||
| Ig strand A' | 37..42 | CDD:409353 | 0/4 (0%) | ||
| Ig strand B | 44..51 | CDD:409353 | 1/6 (17%) | ||
| CDR1 | 51..59 | CDD:409353 | 2/7 (29%) | ||
| Ig strand C | 59..63 | CDD:409353 | 0/3 (0%) | ||
| FR2 | 60..63 | CDD:409353 | 0/2 (0%) | ||
| CDR2 | 67..81 | CDD:409353 | 5/16 (31%) | ||
| Ig strand C' | 68..72 | CDD:409353 | 3/6 (50%) | ||
| Ig strand C' | 79..81 | CDD:409353 | 0/1 (0%) | ||
| FR3 | 84..115 | CDD:409353 | 12/30 (40%) | ||
| Ig strand D | 84..90 | CDD:409353 | 3/5 (60%) | ||
| Ig strand E | 94..102 | CDD:409353 | 2/7 (29%) | ||
| Ig strand F | 108..115 | CDD:409353 | 3/6 (50%) | ||
| CDR3 | 116..124 | CDD:409353 | 0/13 (0%) | ||
| FR4 | 124..130 | CDD:409353 | 2/5 (40%) | ||
| Ig strand G | 124..130 | CDD:409353 | 2/5 (40%) | ||
| Ig_3 | 134..208 | CDD:404760 | 14/79 (18%) | ||
| Ig strand B | 153..157 | CDD:409353 | 0/3 (0%) | ||
| Ig strand C | 166..170 | CDD:409353 | 1/3 (33%) | ||
| Ig strand E | 187..191 | CDD:409353 | 1/3 (33%) | ||
| Ig strand F | 201..206 | CDD:409353 | 1/5 (20%) | ||
| Ig strand G | 215..218 | CDD:409353 | 1/2 (50%) | ||
| Ig | 227..318 | CDD:416386 | 19/106 (18%) | ||
| Ig strand C | 256..260 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 286..290 | CDD:409353 | 0/3 (0%) | ||
| Ig strand F | 300..305 | CDD:409353 | 1/4 (25%) | ||
| SIGLEC7 | NP_055200.1 | Ig_Siglec_N | 26..144 | CDD:143189 | 28/120 (23%) |
| Sialic acid binding. /evidence=ECO:0000269|PubMed:12438315, ECO:0000269|PubMed:16623661, ECO:0000269|PubMed:16895906 | 131..135 | 0/3 (0%) | |||
| Ig | 150..223 | CDD:325142 | 14/80 (18%) | ||
| IG_like | 261..336 | CDD:214653 | 18/90 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 401..431 | ||||
| ITIM motif | 435..440 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 443..467 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||