DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and Cntn5

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_036010831.1 Gene:Cntn5 / 244682 MGIID:3042287 Length:1434 Species:Mus musculus


Alignment Length:366 Identity:98/366 - (26%)
Similarity:144/366 - (39%) Gaps:88/366 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LAQRTPTISYITQEQIKDIGGTVEFDCSVQYA-------KEYNVLFLKTDS-----DP------- 69
            ::|.|..: ||::.|..|:|..:   |.|:.|       .....|.|:.|.     :|       
Mouse   553 ISQETGNL-YISKVQTSDVGSYI---CLVKNAVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFP 613

  Fly    70 --VFLSTGSTLVIKDSRFSL-------------RYDPNSSTYK-----LQIKDIQETDAGTYTCQ 114
              |..:.|:|  :|...|:|             .|.|:.|..:     |:|.::|..|||.|.|.
Mouse   614 FTVTAAKGTT--VKMECFALGNPVPTITWMKVNGYIPSKSRLRKSQAVLEIPNLQLDDAGIYECT 676

  Fly   115 VVISTVHKVSAEVKLSVRRPP--VISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAIL 177
            ...|. .|.|...:|.:...|  |...|.||   ...||.:|.||.|:|.|.||..|.:....:|
Mouse   677 AENSR-GKNSFRGQLQIFTYPHWVQKLNDTQ---LDSGSPLQWECKATGKPRPTYRWLKNGAPLL 737

  Fly   178 PTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAPVITVPRPRLGQ---AL 239
            |......|...|.|:||.:.|.|.|.|:|:|....     |....|...:.:.|...|.|   ::
Mouse   738 PQSRVDTVNGILAIQSVNQSDAGMYQCLAENKYGA-----IYASAELKILASPPSFELNQVKKSI 797

  Fly   240 QYDMD----LECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYT---------------- 284
            ....|    :||..:..|.|||.|.|.|..:..|:  |:|.|:|..:.|                
Mouse   798 IVTKDRGVLIECEPQGSPKPAISWRKGDKAVRANK--SVSFFSTVVQRTRGTCVVMNGWGPKLAR 860

  Fly   285 -------DSTLRVITVEKRQYGDYVCKATNRFGEAEARVNL 318
                   |.:||::...|...|.|:|:..|.||.||...:|
Mouse   861 RRIAILPDGSLRILNASKADEGKYICQGVNIFGSAEIIASL 901

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 31/133 (23%)
FR1 37..50 CDD:409353 3/12 (25%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 0/6 (0%)
CDR1 51..59 CDD:409353 2/14 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/27 (15%)
Ig strand C' 68..72 CDD:409353 2/12 (17%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/48 (27%)
Ig strand D 84..90 CDD:409353 2/18 (11%)
Ig strand E 94..102 CDD:409353 3/12 (25%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 28/75 (37%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 31/120 (26%)
Ig strand C 256..260 CDD:409353 2/3 (67%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Cntn5XP_036010831.1 Ig strand D 741..745 CDD:409353 0/3 (0%)
Ig strand E 747..752 CDD:409353 1/4 (25%)
Ig strand F 761..768 CDD:409353 3/6 (50%)
Ig strand G 772..781 CDD:409353 2/13 (15%)
Ig 786..903 CDD:416386 32/118 (27%)
Ig strand A 786..791 CDD:409353 1/4 (25%)
Ig strand A' 794..799 CDD:409353 0/4 (0%)
Ig strand B 803..810 CDD:409353 1/6 (17%)
Ig strand C 818..822 CDD:409353 2/3 (67%)
Ig strand D 865..868 CDD:409353 0/2 (0%)
Ig strand E 869..874 CDD:409353 2/4 (50%)
Ig strand F 882..890 CDD:409353 3/7 (43%)
Ig strand G 896..903 CDD:409353 2/6 (33%)
Ig 905..1006 CDD:416386
Ig strand A 905..911 CDD:409353
Ig strand A' 914..919 CDD:409353
Ig strand B 922..930 CDD:409353
Ig strand C 939..943 CDD:409353
Ig strand D 964..967 CDD:409353
Ig strand E 968..972 CDD:409353
Ig strand F 981..988 CDD:409353
Ig strand G 995..999 CDD:409353
FN3 1006..1103 CDD:238020
FN3 1111..1203 CDD:238020
FN3 1213..1304 CDD:238020
FN3 1311..1397 CDD:238020
Integrase_Zn 26..62 CDD:396557
rve 78..172 CDD:395538
IN_DBD_C 243..288 CDD:395437
Ig 404..499 CDD:416386
Ig strand A 406..410 CDD:409353
Ig strand A' 413..418 CDD:409353
Ig strand B 424..432 CDD:409353
Ig strand C 437..443 CDD:409353
Ig strand C' 445..448 CDD:409353
Ig strand D 455..459 CDD:409353
Ig strand E 461..467 CDD:409353
Ig strand F 474..483 CDD:409353
Ig strand G 486..499 CDD:409353
Ig 508..593 CDD:416386 10/43 (23%)
Ig strand A 509..514 CDD:409353
Ig strand B 518..524 CDD:409353
Ig strand C 532..538 CDD:409353
Ig strand C' 543..545 CDD:409353
Ig strand D 550..555 CDD:409353 0/1 (0%)
Ig strand E 558..562 CDD:409353 0/4 (0%)
Ig strand F 572..580 CDD:409353 2/10 (20%)
Ig strand G 582..593 CDD:409353 0/10 (0%)
Ig 606..693 CDD:416386 22/89 (25%)
Ig strand A 606..611 CDD:409353 1/4 (25%)
Ig strand A' 614..619 CDD:409353 1/4 (25%)
Ig strand B 622..631 CDD:409353 3/10 (30%)
Ig strand C 637..641 CDD:409353 0/3 (0%)
Ig strand C' 644..646 CDD:409353 0/1 (0%)
Ig strand D 654..657 CDD:409353 0/2 (0%)
Ig strand E 658..663 CDD:409353 1/4 (25%)
Ig strand F 671..679 CDD:409353 3/7 (43%)
Ig strand G 682..693 CDD:409353 3/10 (30%)
Ig 698..781 CDD:416386 30/90 (33%)
Ig strand A' 704..708 CDD:409353 2/6 (33%)
Ig strand B 712..720 CDD:409353 3/7 (43%)
Ig strand C 726..731 CDD:409353 2/4 (50%)
Ig strand C' 733..736 CDD:409353 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.