DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and zig-3

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_509336.1 Gene:zig-3 / 192088 WormBaseID:WBGene00006980 Length:251 Species:Caenorhabditis elegans


Alignment Length:230 Identity:48/230 - (20%)
Similarity:76/230 - (33%) Gaps:78/230 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 ISDNSTQSVVASEGSEVQMECYASGYPTPTITWRREN----------------NAILPTDSATYV 185
            :.||:     .|.|..|.:.|.....||..|.|.::.                ||:.||..:..:
 Worm    50 LEDNT-----VSTGESVTLRCDVLSTPTGVIYWEKDGQRIQGDKELNVFEKVLNAMGPTVESGII 109

  Fly   186 GNTLRIKSVKKEDRGTYYCVADNG---------VS--------KGDRRNINVEVEFAPVITVPRP 233
            .::.:|........|:|.|||.||         :|        |..||:       |||||    
 Worm   110 TSSYQIPCANLHHIGSYKCVATNGHDTVESSAKISV
EGQTVKCKSTRRS-------APVIT---- 163

  Fly   234 RLGQALQYDMDLECHIEAYPPPAIV-----------WTKDDIQL-ANNQHYSISHFATADEYTDS 286
                     |..|...|.....|.:           |..:|.:: .::..|.:        ....
 Worm   164 ---------MSTESRFELQDNAATLICRADRRANWNWMFEDKKIDFDSGRYEL--------LPSG 211

  Fly   287 TLRVITVEKRQYGDYVCKATNRFGEAEARVNLFET 321
            .|.:..::....|.|.|.|.|::||:.....|:.|
 Worm   212 DLLIRKIQWSDMGSYFCIAHNKYGESRGETFLYPT 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353
Ig strand F 108..115 CDD:409353
CDR3 116..124 CDD:409353
FR4 124..130 CDD:409353
Ig strand G 124..130 CDD:409353
Ig_3 134..208 CDD:404760 20/86 (23%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 2/2 (100%)
Ig 227..318 CDD:416386 18/102 (18%)
Ig strand C 256..260 CDD:409353 1/14 (7%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
zig-3NP_509336.1 I-set 45..145 CDD:254352 22/99 (22%)
Ig 61..142 CDD:143165 18/80 (23%)
IG_like 177..244 CDD:214653 12/74 (16%)
Ig <191..237 CDD:299845 10/53 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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