DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and zig-10

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001122644.1 Gene:zig-10 / 188896 WormBaseID:WBGene00020800 Length:322 Species:Caenorhabditis elegans


Alignment Length:255 Identity:60/255 - (23%)
Similarity:98/255 - (38%) Gaps:75/255 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   119 TVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSAT 183
            |:|.::.:...:.|..|:             ||...:||  ..|.:..:||.|:.:.|     ||
 Worm    21 TIHTLAPKKAPTERLVPI-------------GSTTALEC--EPYTSSNVTWYRDKHVI-----AT 65

  Fly   184 YVGNT---------------------LRIKSVKKEDRGTYYCVADNGVSKG----------DRRN 217
            ..|:.                     |.|..|:|||.|.|||..:|....|          |..:
 Worm    66 VEGHKNAILNERKPRGGEERIPEIGFLVIFDVQKEDEGNYYCQRENDSKWGEVFQLKIAYVDEIS 130

  Fly   218 INVEVEFAPVITVPRPRLGQALQYDMDLECHI-EAYPPPAIVWTKDDIQLANNQHYSISHFATAD 281
            .|.:::..|.:    |.||::|.    |.|.| :|||||.:.||.:.:.::   |.|..:.|   
 Worm   131 QNEKIKLEPNV----PTLGRSLV----LHCPIPKAYPPPKVTWTVNSLPIS---HISSDYVA--- 181

  Fly   282 EYTDSTLRVITVEKRQYGDYVCK--------ATNRFGEAEARVNLFETIIPVCPPACGQA 333
             :.:.||.:.......:|.:.|.        :||.|.::...|...|::.|.....|..|
 Worm   182 -FPNGTLIISHFSYHHFGYFECNINNFAGHASTNTFIDSRELVANLESLKPTFVNGCSAA 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 2/11 (18%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353
Ig strand F 108..115 CDD:409353
CDR3 116..124 CDD:409353 2/4 (50%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 23/94 (24%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/24 (4%)
Ig strand F 201..206 CDD:409353 3/4 (75%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 25/99 (25%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 1/12 (8%)
zig-10NP_001122644.1 IG_like 31..118 CDD:214653 26/106 (25%)
IGc2 38..111 CDD:197706 22/92 (24%)
IG_like 143..215 CDD:214653 21/82 (26%)
IGc2 145..209 CDD:197706 19/74 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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