DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and zig-4

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_509335.1 Gene:zig-4 / 181051 WormBaseID:WBGene00006981 Length:253 Species:Caenorhabditis elegans


Alignment Length:240 Identity:51/240 - (21%)
Similarity:85/240 - (35%) Gaps:54/240 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 VISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWR---------R 171
            |::..:::......|..:..:::  ..:|.:...|...|:.|.....|..||.|:         .
 Worm    28 VVTLANEIDTNYLTSPAKIKIVA--PLESALIPGGETYQLRCDIMSTPAATIHWKFNGKLIQGSN 90

  Fly   172 ENN----------AILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVS----------KGDRR 216
            |.|          ||:.|.   .|.:.|.|:....|:.|||.||..||..          :|:..
 Worm    91 ELNVEEKLLNFGKAIVDTG---IVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEAS 152

  Fly   217 NINVEVEFAPVITVPRPRLGQALQYDM-----DLECHIEAYPPPAIVWTKDDIQLANNQHYSISH 276
            ......:.||.|.     .....:::|     .|.|  .|......||..:|..:.||..:::  
 Worm   153 GCRSNHKSAPEIV-----FWTDSRFEMTGNVATLVC--RANQQVDWVWMSNDELVKNNDKFTV-- 208

  Fly   277 FATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFET 321
                  .::..|.:..:.....|.|.|.|.|:||||.....|:.|
 Worm   209 ------LSNGDLVIKNIVWDDMGTYTCIARNQFGEARQETFLYPT 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 1/14 (7%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353
Ig strand F 108..115 CDD:409353
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 22/92 (24%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 3/4 (75%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 20/95 (21%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
zig-4NP_509335.1 I-set 47..147 CDD:254352 24/104 (23%)
Ig 65..144 CDD:143165 21/81 (26%)
IG_like 176..245 CDD:214653 18/78 (23%)
Ig <193..238 CDD:299845 12/52 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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