DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and AgaP_AGAP010884

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_309810.4 Gene:AgaP_AGAP010884 / 1271065 VectorBaseID:AGAP010884 Length:1951 Species:Anopheles gambiae


Alignment Length:321 Identity:84/321 - (26%)
Similarity:126/321 - (39%) Gaps:73/321 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 KTDS---DPVFLSTGSTLVIKDSRFSLRYD---PNSSTYK-----------------------LQ 99
            ||.|   .|:|....|.|.:    ..|...   ||...||                       |.
Mosquito   229 KTPSLTQKPIFADPNSDLAL----LCLAQGFPAPNFRWYKYIEGTQQKKAVVLDDRVKQVSGTLI 289

  Fly   100 IKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVIS-DNSTQSVVASEGSEVQMECYASGYP 163
            |||....|:|.|.| ||.::|...|.|..|:|..|.... :..||:|  ..|......|..||.|
Mosquito   290 IKDAVVDDSGKYLC-VVNNSVGGESVETVLTVTAPLAAKIEPRTQTV--DFGRPAVFTCKFSGNP 351

  Fly   164 TPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEF---- 224
            ..|::|.::..::..:|:      .|||:||||||:|.|.|...|     |:.:.....|.    
Mosquito   352 IKTVSWMKDGKSLGHSDA------VLRIESVKKEDKGMYQCFIRN-----DQESAQASAELKLGG 405

  Fly   225 ---APVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDS 286
               .|:|....|...:.....:.|:|.....|.|.|.|..|..::.|::.|.:..:.|.:....|
Mosquito   406 RFDPPIIREAFPEETRHPGPSVFLKCVAGGNPTPEISWELDGKKITNSERYQVGQYVTVNGDVVS 470

  Fly   287 TLRVITVEKRQYGDYVCKATNRFGEAE--ARVNLF----------------ETIIPVCPPA 329
            .|.:.::.....|.|.|.|:::.|.||  |::|::                ||:|..||.|
Mosquito   471 HLNITSIHSNDGGLYKCMASSKVGVAEHSAKLNVYGLPYVRTMEKKAIVAGETLIVTCPVA 531

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 26/95 (27%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353 5/16 (31%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/56 (23%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 4/30 (13%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 2/5 (40%)
Ig strand G 124..130 CDD:409353 2/5 (40%)
Ig_3 134..208 CDD:404760 24/74 (32%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 22/92 (24%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
AgaP_AGAP010884XP_309810.4 Ig 16..110 CDD:299845
IG_like 35..106 CDD:214653
I-set 231..320 CDD:254352 24/93 (26%)
Ig 248..317 CDD:143165 18/73 (25%)
I-set 328..402 CDD:254352 26/86 (30%)
IGc2 338..390 CDD:197706 20/57 (35%)
IG_like 417..504 CDD:214653 21/86 (24%)
IGc2 423..494 CDD:197706 16/70 (23%)
I-set 510..593 CDD:254352 6/22 (27%)
IGc2 521..584 CDD:197706 6/11 (55%)
Ig 619..689 CDD:143165
I-set 696..788 CDD:254352
Ig 715..788 CDD:299845
I-set 794..889 CDD:254352
Ig 808..896 CDD:299845
FN3 893..987 CDD:238020
FN3 994..1094 CDD:238020
FN3 1102..1195 CDD:238020
FN3 1200..1288 CDD:238020
Ig 1315..1382 CDD:299845
FN3 1386..1475 CDD:238020
FN3 1480..1560 CDD:238020
Dscam_C 1858..1949 CDD:289151
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.