DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Hepacam2

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_006505020.1 Gene:Hepacam2 / 101202 MGIID:2141520 Length:464 Species:Mus musculus


Alignment Length:276 Identity:74/276 - (26%)
Similarity:113/276 - (40%) Gaps:54/276 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    61 LFLKTDSDPVFLSTGST--LVIKDSRFSLRY---DPNSSTYKLQIKDIQETDAGTYTCQVVISTV 120
            ||.::.:.|.:| .||.  .|:.|..:..::   .||:|   |.|..:|.||.|.|..:|.|...
Mouse    71 LFERSHTMPKYL-LGSVNKSVVPDLEYQHKFTMMPPNAS---LLINPLQFTDEGNYIVKVNIQGN 131

  Fly   121 HKVSAEVKLSVR-----RPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTD 180
            ..:||..|:.|.     ..|::..:.....|...|: :.:.|...|.......||:....|....
Mouse   132 GTLSASQKIQVTV
DDPVMKPMVQFHPASGAVEYVGN-ITLTCQVEGGTRLVYQWRKSGKPISINS 195

  Fly   181 SATY--VGNTLRIKSVKKEDRGTYYCVADNGVSKGDRRNINVEVEFAP---------------VI 228
            |.::  ..|||.|..|.|||.|.|.|:..|.||:.:...|...:.:.|               |.
Mouse   196 SHSFSPQNNTLWIVPVTKEDIGNYTCLVSNPVSEMESDI
IMPTIYYGPYGLQVNSDKGLKVGEVF 260

  Fly   229 TVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITV 293
            ||.   ||:|:.:|    |..::|||....|    ||.::|..:.|.|....:         :..
Mouse   261 TVD---LGEAVLFD----CSADSYPPNTYSW----IQRSDNTTHVIKHGPHLE---------VAS 305

  Fly   294 EK--RQYGDYVCKATN 307
            ||  ::..||||.|.|
Mouse   306 EKVAQKTADYVCCAYN 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 23/74 (31%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353 1/1 (100%)
FR2 60..63 CDD:409353 1/1 (100%)
CDR2 67..81 CDD:409353 5/15 (33%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 1/1 (100%)
FR3 84..115 CDD:409353 10/33 (30%)
Ig strand D 84..90 CDD:409353 0/8 (0%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 3/5 (60%)
Ig strand G 124..130 CDD:409353 3/5 (60%)
Ig_3 134..208 CDD:404760 20/75 (27%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 3/3 (100%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 25/83 (30%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 4/4 (100%)
Hepacam2XP_006505020.1 Ig 37..144 CDD:386229 24/76 (32%)
Ig 168..234 CDD:319273 20/65 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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