DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and igsf9b

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_031761656.1 Gene:igsf9b / 100379858 XenbaseID:XB-GENE-5887265 Length:1392 Species:Xenopus tropicalis


Alignment Length:365 Identity:90/365 - (24%)
Similarity:144/365 - (39%) Gaps:66/365 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VWSTLLLAIFVQQTL---------AQRTPTISYITQEQIKDIGGTVEFDCSVQY-----AKEYNV 60
            :|..|.|...|..||         ::..|  .::|..    .|.:|...|.|.:     ...|.|
 Frog     2 IWYVLTLIASVISTLGLSVQGAGGSREEP--QFVTAR----AGESVILGCDVVHPLTVQPPPYVV 60

  Fly    61 LFLKTDSD-PVFLSTGSTLVIKDSRFSLR---YDPNSSTYKLQIKDIQETDAGTYTCQVVI---- 117
            .:.|.... |:|:..|......|..:..|   ||..|    |:|:.::..|.|.|.|:|::    
 Frog    61 EWFKFGVPIPIFIKFGFYPPHVDPEYVGRAALYDKAS----LRIEQVRSQDQGWYECKVLMLEHQ 121

  Fly   118 -STVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDS 181
             .|.|. .:.|.|:|..||..::...|.:...|||.:.:.|.|.|.|.||::|.||...:..|..
 Frog   122 YDTFHN-GSWVHLTVNAPPTFTETPPQYLEVKEGSSITLTCTAFGNPKPTVSWLREGEFLGRTSK 185

  Fly   182 ATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDR-RNINVEVEFAPVITVPRPRLGQALQYDMDL 245
            ......:|.|.|:.:||||:|.|.|.:  .:|:. .:..:.|:.:|.|..|...:...:..|...
 Frog   186 YQLSDGSLTISSIGREDRGSYMCRATS--IQGEAVHSTRLLVQGSPFIVSPPENITVNISQDALF 248

  Fly   246 ECHIEAYPPPAI---VWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATN 307
            .|..||||....   .|.::::...|:....:...      .|.||.:..|:....|.|.|..:|
 Frog   249 TCQAEAYPGNLTYTWYWQEENVFFKNDLKLRVRIL------IDGTLIIFRVKPEDAGKYTCVPSN 307

  Fly   308 RFGEAEAR------------VNLFETI-IPV-------CP 327
            ..|.:.:.            ||:...| :||       ||
 Frog   308 SLGRSPSASAYLTVQYPARVVNMPPVIYVPVGIHGHIRCP 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 26/108 (24%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/12 (8%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/14 (21%)
Ig strand C' 68..72 CDD:409353 1/4 (25%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 10/33 (30%)
Ig strand D 84..90 CDD:409353 1/8 (13%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 2/12 (17%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 26/73 (36%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/3 (0%)
Ig 227..318 CDD:416386 20/105 (19%)
Ig strand C 256..260 CDD:409353 0/6 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
igsf9bXP_031761656.1 IG 30..115 CDD:214652 23/94 (24%)
I-set 139..225 CDD:400151 26/87 (30%)
Ig strand A 139..142 CDD:409353 1/2 (50%)
Ig strand A' 148..151 CDD:409353 0/2 (0%)
Ig strand B 157..164 CDD:409353 1/6 (17%)
Ig strand C 170..175 CDD:409353 2/4 (50%)
Ig strand D 185..189 CDD:409353 0/3 (0%)
Ig strand E 191..195 CDD:409353 1/3 (33%)
Ig strand F 204..212 CDD:409353 4/7 (57%)
Ig strand G 215..225 CDD:409353 1/9 (11%)
I-set 229..321 CDD:400151 20/97 (21%)
Ig strand B 246..250 CDD:409353 0/3 (0%)
Ig strand C 260..264 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
Ig strand G 314..317 CDD:409353 0/2 (0%)
Ig 344..405 CDD:409353 2/4 (50%)
Ig strand C 355..360 CDD:409353
Ig strand E 380..384 CDD:409353
Ig strand F 394..399 CDD:409353
Ig 429..505 CDD:416386
Ig strand A' 429..432 CDD:409353
Ig strand B 438..445 CDD:409353
Ig strand C 451..456 CDD:409353
Ig strand C' 458..460 CDD:409353
Ig strand E 471..476 CDD:409353
Ig strand F 484..492 CDD:409353
Ig strand G 495..505 CDD:409353
FN3 510..605 CDD:238020
FN3 622..703 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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