DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and Kirrel2

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_038957463.1 Gene:Kirrel2 / 100359836 RGDID:1308456 Length:711 Species:Rattus norvegicus


Alignment Length:376 Identity:86/376 - (22%)
Similarity:131/376 - (34%) Gaps:102/376 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 GTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVI----------KDS--RFSLRYDPNSSTY 96
            ||||           |.|||...|.    ..|:||:.          :|:  ..||:|.| ..|.
  Rat   191 GTVE-----------NTLFLTPSSQ----DDGATLICRARSQALPTGRDTAVTLSLQYPP-MVTL 239

  Fly    97 KLQIKDIQETDAGTYTCQVVIS-------------------------------TVHKVSAEVK-- 128
            ..:.:..||.:..|:.||....                               ....||.||.  
  Rat   240 SAEPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNA 304

  Fly   129 ---------LSVRRPPVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATY 184
                     |.|...|:: ....:.|....|.:....|...|.|.|.|:|.|     |.......
  Rat   305 VGSANRSTALEVLYGPIL-QAKPKPVSVDVGKDASFSCVWRGNPLPRISWTR-----LGGSQVLS 363

  Fly   185 VGNTLRIKSVKKEDRGTYYCVAD---NGVSKGDRRNINVEVEFAPVITV--PRPRLGQALQYDMD 244
            .|.|||:.||..||.|.|.|.|:   .||. |......:.|...||:|.  |.|..   |:....
  Rat   364 SGPTLRLPSVALEDAGDYVCRAEPRRTGVG-GGTAQARLTVNAPPVVTALHPAPAF---LRGPAR 424

  Fly   245 LECHIEAYP-PPAIVWTKDD--IQLANNQHYSISHFATAD---EYTDSTLRVITVEKRQYGDYV- 302
            |:|.:.|.| |.::||:.|:  ::..:...:.:..|...:   ......:.|:.:...|..|:. 
  Rat   425 LQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTT 489

  Fly   303 ---CKATNRFGEAEARVNL-FETIIPVCPPACGQAYIAGAEDVSATSFALV 349
               |.|.||.||...:::| ...::|..      ..:|||...:.:.|.::
  Rat   490 GFNCSARNRLGEGRVQIHLGRRDLLPTV------RLVAGAASAATSLFMVI 534

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 28/140 (20%)
FR1 37..50 CDD:409353 4/5 (80%)
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 4/6 (67%)
CDR1 51..59 CDD:409353 0/7 (0%)
Ig strand C 59..63 CDD:409353 2/3 (67%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/23 (17%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/11 (0%)
FR3 84..115 CDD:409353 9/30 (30%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 1/7 (14%)
Ig strand F 108..115 CDD:409353 2/6 (33%)
CDR3 116..124 CDD:409353 0/38 (0%)
FR4 124..130 CDD:409353 3/16 (19%)
Ig strand G 124..130 CDD:409353 3/16 (19%)
Ig_3 134..208 CDD:404760 23/76 (30%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 2/3 (67%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 23/102 (23%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/8 (25%)
Kirrel2XP_038957463.1 IG_like 38..127 CDD:214653
Ig strand A' 40..44 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand C 62..66 CDD:409353
Ig strand D 75..85 CDD:409353
Ig strand E 88..100 CDD:409353
Ig strand F 107..115 CDD:409353
Ig strand G 117..127 CDD:409353
Ig 133..231 CDD:416386 13/54 (24%)
Ig strand A 134..137 CDD:409353
Ig strand A' 140..144 CDD:409353
Ig strand B 151..158 CDD:409353
Ig strand C 164..169 CDD:409353
Ig strand C' 172..174 CDD:409353
Ig strand D 177..184 CDD:409353
Ig strand E 191..199 CDD:409353 6/18 (33%)
Ig strand F 208..216 CDD:409353 2/7 (29%)
Ig strand G 222..228 CDD:409353 1/5 (20%)
Ig_3 234..303 CDD:404760 11/69 (16%)
Ig strand B 252..256 CDD:409353 1/3 (33%)
Ig strand C 266..270 CDD:409353 0/3 (0%)
Ig strand E 283..286 CDD:409353 0/2 (0%)
Ig strand F 292..301 CDD:409353 2/8 (25%)
Ig strand G 309..312 CDD:409353 0/2 (0%)
Ig 326..403 CDD:416386 25/82 (30%)
Ig strand A' 327..332 CDD:409353 1/4 (25%)
Ig strand B 335..344 CDD:409353 1/8 (13%)
Ig strand C 350..354 CDD:409353 1/3 (33%)
Ig strand C' 357..359 CDD:409353 0/1 (0%)
Ig strand D 362..365 CDD:409353 0/2 (0%)
Ig strand E 366..371 CDD:409353 3/4 (75%)
Ig strand F 379..387 CDD:409353 4/7 (57%)
Ig strand G 393..403 CDD:409353 1/10 (10%)
Ig 405..509 CDD:416386 24/106 (23%)
Ig strand A 406..410 CDD:409353 2/3 (67%)
Ig strand A' 412..415 CDD:409353 0/2 (0%)
Ig strand B 423..430 CDD:409353 2/6 (33%)
Ig strand C 437..442 CDD:409353 2/4 (50%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 455..462 CDD:409353 1/6 (17%)
Ig strand E 472..479 CDD:409353 1/6 (17%)
Ig strand F 490..497 CDD:409353 2/6 (33%)
Ig strand G 500..507 CDD:409353 2/6 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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