DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and si:ch211-74m13.1

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_001922015.4 Gene:si:ch211-74m13.1 / 100149459 ZFINID:ZDB-GENE-081104-12 Length:328 Species:Danio rerio


Alignment Length:265 Identity:47/265 - (17%)
Similarity:95/265 - (35%) Gaps:72/265 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 CQVVIS-TVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQMEC---YASGYPTPTITWRREN 173
            |:|.:. |::|....|.:           ||.:.:.:||::.:::|   ..:.....||.|.:..
Zfish    97 CEVPLPVTIYKTPDSVSI-----------STVNQIMTEGNQYELQCDIHNVAPAQNLTINWYKGE 150

  Fly   174 NAILPTDSATYVGNT---------LRIKSVKKEDRGTYYCVADNGVS--------KGDRRNINVE 221
            ..:..|:   :..||         |.|...:.:|...|.|..:..:.        |...:.::::
Zfish   151 TLVNQTN---FTDNTKSPVNKIIRLLIHPDRADDGAQYRCETELNLGVEGPQPPPKNTSKPLSID 212

  Fly   222 VEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDS 286
            |.:.|..:.....:.|:  ..:.|.|.::|.|.....|..:.::                |...|
Zfish   213 VHYKPQHSSSAENISQS--DTVYLNCTVKANPAAVYTWHSEHLK----------------EKISS 259

  Fly   287 TLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQAYIAGAEDVSATSFALVGI 351
            .  ||.......|.|.|.|||..| |.::|.:                ::.|...:..:..:.|:
Zfish   260 P--VIQSSPLSPGKYTCTATNDLG-ASSKVFI----------------VSSAGRTTFWAIVIAGV 305

  Fly   352 LAALL 356
            :.|:|
Zfish   306 VLAVL 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 5/18 (28%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353
Ig strand C' 68..72 CDD:409353
Ig strand C' 79..81 CDD:409353
FR3 84..115 CDD:409353 1/1 (100%)
Ig strand D 84..90 CDD:409353
Ig strand E 94..102 CDD:409353
Ig strand F 108..115 CDD:409353 1/1 (100%)
CDR3 116..124 CDD:409353 2/8 (25%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 16/85 (19%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 3/12 (25%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 19/90 (21%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
si:ch211-74m13.1XP_001922015.4 Ig2_ICAM-1_like 109..209 CDD:143232 18/113 (16%)
Ig_2 217..281 CDD:290606 17/83 (20%)
IG_like 230..281 CDD:214653 15/68 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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