DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lac and lrit3b

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_009305418.1 Gene:lrit3b / 100144406 ZFINID:ZDB-GENE-070424-130 Length:487 Species:Danio rerio


Alignment Length:298 Identity:64/298 - (21%)
Similarity:106/298 - (35%) Gaps:117/298 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 SVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSS--TYKLQIKDIQETDAGTYTC 113
            :|:|.:  ||.:|...|:.:     |||....:...|..|.|.:  ::.|.::|      ..:.|
Zfish   179 AVRYLR--NVTYLDLSSNRL-----STLANDLTALWLFSDSNQTQRSFVLGLQD------NPWVC 230

  Fly   114 QVVISTVHKVS---------------------------AEVKLS-VRRPPVISDNSTQSVVASEG 150
            ...:||:..:|                           ..|:|| .|||.|::  |...:.|..|
Zfish   231 DCRLSTLLDISRGPESSLVLLDRFLTCSEPLDLAGVPFQSVELSRCRRPYVVT--SATKITALLG 293

  Fly   151 SEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDRGTYYCVADNGVSKGDR 215
            |.|.:.|.|:|:|||.:.|                     |||.|   |..|    :.|..|..:
Zfish   294 STVLLRCEATGHPTPALMW---------------------IKSAK---RNLY----NQGCCKQTQ 330

  Fly   216 RNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISHFATA 280
            .:::.|       ..|:...|           :::..|...:.|:...:.       .||     
Zfish   331 SSLDTE-------RFPKKLFG-----------YVQESPRVGVRWSVVSLN-------GIS----- 365

  Fly   281 DEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNL 318
              |:|:            |:|.|:|.|..|.:||.|:|
Zfish   366 --YSDA------------GEYRCRAQNMAGISEAVVSL 389

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 21/109 (19%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 64/298 (21%)
CDR1 51..59 CDD:409353 2/7 (29%)
Ig strand C 59..63 CDD:409353 2/3 (67%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 4/13 (31%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 6/32 (19%)
Ig strand D 84..90 CDD:409353 1/5 (20%)
Ig strand E 94..102 CDD:409353 1/9 (11%)
Ig strand F 108..115 CDD:409353 1/6 (17%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 2/32 (6%)
Ig strand G 124..130 CDD:409353 2/32 (6%)
Ig_3 134..208 CDD:404760 20/73 (27%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 0/3 (0%)
Ig strand E 187..191 CDD:409353 0/3 (0%)
Ig strand F 201..206 CDD:409353 1/4 (25%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 17/90 (19%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
lrit3bXP_009305418.1 LRRNT 51..92 CDD:214470
leucine-rich repeat 69..89 CDD:275380
LRR_8 112..172 CDD:290566
leucine-rich repeat 114..137 CDD:275378
leucine-rich repeat 138..161 CDD:275378
LRR_8 160..214 CDD:290566 11/41 (27%)
LRR_4 160..201 CDD:289563 9/28 (32%)
leucine-rich repeat 162..185 CDD:275378 2/7 (29%)
leucine-rich repeat 186..199 CDD:275378 4/17 (24%)
leucine-rich repeat 215..230 CDD:275378 2/20 (10%)
Ig 278..391 CDD:299845 42/186 (23%)
I-set 279..391 CDD:254352 41/185 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.