DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and lsamp

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_031751462.1 Gene:lsamp / 100124984 XenbaseID:XB-GENE-5759171 Length:368 Species:Xenopus tropicalis


Alignment Length:351 Identity:100/351 - (28%)
Similarity:148/351 - (42%) Gaps:56/351 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 ITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYDPNSS---- 94
            ||..|    |.|....|.|:          ...|...:|:....:...|.::||  ||...    
 Frog    41 ITVRQ----GDTAILRCFVE----------DRSSRVAWLNRSGIIFAGDDKWSL--DPRVELEKR 89

  Fly    95 ---TYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRPPVISDNSTQSVVASEGSEVQME 156
               .|.|:|:.:..:|.|.|||.|. :..|..:.:|.|.|:.||.|| |.:..:..:|||.|.:.
 Frog    90 SLLEYSLRIQKVDVSDEGPYTCSVQ-TKQHTKTTQVYLIVQVPPKIS-NISADITVNEGSNVTLM 152

  Fly   157 CYASGYPTPTITWRRENNAILPTDSAT----YVGNT--LRIKSVKKEDRGTYYCVADNGVSKGDR 215
            |.|.|.|.|.||||.    :.||...:    :.|..  |.|:.:.:|..|.|.|.|.|.|:..|.
 Frog   153 CIAYGRPEPMITWRH----LTPTAGTSPARDFEGEEEFLEIQGITREQSGRYECKAANEVASADV 213

  Fly   216 RNINVEVEFAPVITVPRPRLG----QALQYDMDLECHIEAYPPPAIVWTKDDIQLANNQHYSISH 276
            :.:.|.|.:.|:||..:....    ||:     |.|...|.|.|...|.|||.:  :.:..|...
 Frog   214 KQVRVTVNYPPIITESKSNEATTGKQAI-----LRCEASAVPAPDFEWYKDDTR--SRRINSAQG 271

  Fly   277 FATADEYTDSTLRVITVEKRQYGDYVCKATNRFGEAEARVNLFETIIPVCPPACGQ-------AY 334
            ....:..:.|.|.|..|.:..||:|.|.|.|:.|.....:.|::.:.|..|.:..:       .|
 Frog   272 LEIRNTGSRSVLMVANVTEEHYGNYTCVAANKLGITNTSLYLYKRVSPTKPMSASERGSNVHYQY 336

  Fly   335 IAGAEDV--SATSFAL-VGILAALLF 357
            ..|....  ||||.|. :.::|.|||
 Frog   337 KVGPGTPIDSATSLAASLWLMANLLF 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 24/101 (24%)
FR1 37..50 CDD:409353 3/12 (25%)
Ig strand A' 37..42 CDD:409353 1/4 (25%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 2/13 (15%)
Ig strand C' 68..72 CDD:409353 0/3 (0%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 12/37 (32%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 3/14 (21%)
Ig strand F 108..115 CDD:409353 4/6 (67%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/5 (20%)
Ig strand G 124..130 CDD:409353 1/5 (20%)
Ig_3 134..208 CDD:404760 28/79 (35%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 1/5 (20%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 25/94 (27%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
lsampXP_031751462.1 Ig 38..128 CDD:416386 26/103 (25%)
FR1 38..54 CDD:409353 5/16 (31%)
Ig strand A' 39..45 CDD:409353 2/3 (67%)
Ig strand B 47..55 CDD:409353 2/7 (29%)
CDR1 55..59 CDD:409353 1/13 (8%)
FR2 60..67 CDD:409353 2/6 (33%)
Ig strand C 60..66 CDD:409353 1/5 (20%)
CDR2 68..78 CDD:409353 1/9 (11%)
Ig strand C' 70..73 CDD:409353 0/2 (0%)
Ig strand C' 75..78 CDD:409353 1/2 (50%)
FR3 79..114 CDD:409353 12/36 (33%)
Ig strand D 83..90 CDD:409353 0/6 (0%)
Ig strand E 93..99 CDD:409353 2/5 (40%)
Ig strand F 106..114 CDD:409353 4/7 (57%)
CDR3 115..119 CDD:409353 0/3 (0%)
Ig strand G 119..128 CDD:409353 2/8 (25%)
FR4 121..128 CDD:409353 2/6 (33%)
Ig_3 131..206 CDD:404760 28/79 (35%)
Ig strand A' 138..143 CDD:409353 0/4 (0%)
Ig strand B 149..156 CDD:409353 2/6 (33%)
Ig strand C 162..167 CDD:409353 3/4 (75%)
Ig strand C' 173..175 CDD:409353 0/1 (0%)
Ig strand E 185..191 CDD:409353 2/5 (40%)
Ig strand F 198..205 CDD:409353 3/6 (50%)
Ig strand G 212..220 CDD:409353 2/7 (29%)
Ig_3 223..302 CDD:404760 24/85 (28%)
putative Ig strand A 224..230 CDD:409353 3/5 (60%)
Ig strand B 240..244 CDD:409353 2/8 (25%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 2/3 (67%)
Ig strand F 295..300 CDD:409353 2/4 (50%)
Ig strand G 308..311 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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