DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and igsf9

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:NP_001090640.1 Gene:igsf9 / 100036605 XenbaseID:XB-GENE-989817 Length:1423 Species:Xenopus tropicalis


Alignment Length:349 Identity:78/349 - (22%)
Similarity:119/349 - (34%) Gaps:86/349 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 FDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLV------------------------------IKD 82
            |.|.:..|       :::||..|....|.:.|                              ||.
 Frog    13 FSCCINGA-------IRSDSQTVVGRVGESTVLGCSLLHQDAGRPPLYVIEWVRFGFMLPIFIKF 70

  Fly    83 SRFSLRYDPN-------SSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAE------VKLSVRRP 134
            ..:|.|.||.       .....|.|:.::..|.|.|.|:|:....|....:      |.|:|..|
 Frog    71 GLYSPRVDPQYLGRTRIEEGASLHIESLRSEDQGWYECRVLFLDRHHGEEDFQNGTWVHLTVNSP 135

  Fly   135 PVISDNSTQSVVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSATYVGNTLRIKSVKKEDR 199
            |...:.....|....|..:.:.|.|.|.|.|.:||:|:...:...|.......:|.|..|::.:.
 Frog   136 PSFRETPPTYVEVRVGDTLTLTCVAYGNPQPVVTWKRDGVTLESGDKVQASNGSLSIVGVERGNA 200

  Fly   200 GTYYCVA--DNG-VSKGDRRNINVEVEFAPVITVPRPRLGQALQYDMDLECHIEAYPPP-AIVWT 260
            |.|.|.|  |.| |:...|    |.|:..|:|.||.......:..|..|.|..||||.. ...|.
 Frog   201 GVYTCHAFSDEGEVTHTSR----VLVQGPPIIVVPPENTTVNVSQDAFLTCQAEAYPANLTYTWF 261

  Fly   261 K--DDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATN---RFGEAEARVNLF- 319
            :  :::.|.|.....:...      .|.:..:..|.....|.|.|..:|   :...|.|.:.:. 
 Frog   262 QGSNNVFLLNRLQPRVRIL------VDGSFLIQRVTPEDAGKYTCIPSNGMWKSPSASAYLTVLH 320

  Fly   320 ---------ETIIPV-------CP 327
                     ||.:|:       ||
 Frog   321 PAYVTSMPAETYLPIGMRGVIKCP 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 24/125 (19%)
FR1 37..50 CDD:409353 1/1 (100%)
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353 1/2 (50%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 0/3 (0%)
FR2 60..63 CDD:409353 0/2 (0%)
CDR2 67..81 CDD:409353 4/43 (9%)
Ig strand C' 68..72 CDD:409353 1/3 (33%)
Ig strand C' 79..81 CDD:409353 1/31 (3%)
FR3 84..115 CDD:409353 10/37 (27%)
Ig strand D 84..90 CDD:409353 2/5 (40%)
Ig strand E 94..102 CDD:409353 2/7 (29%)
Ig strand F 108..115 CDD:409353 3/6 (50%)
CDR3 116..124 CDD:409353 1/7 (14%)
FR4 124..130 CDD:409353 1/11 (9%)
Ig strand G 124..130 CDD:409353 1/11 (9%)
Ig_3 134..208 CDD:404760 20/75 (27%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 1/2 (50%)
Ig 227..318 CDD:416386 21/96 (22%)
Ig strand C 256..260 CDD:409353 0/3 (0%)
Ig strand E 286..290 CDD:409353 0/3 (0%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
igsf9NP_001090640.1 Ig 25..132 CDD:299845 20/106 (19%)
IG_like 25..110 CDD:214653 16/84 (19%)
I-set 136..222 CDD:254352 24/89 (27%)
IGc2 151..212 CDD:197706 18/60 (30%)
Ig_2 226..318 CDD:290606 22/97 (23%)
I-set 226..318 CDD:254352 22/97 (23%)
IG_like 328..407 CDD:214653 5/17 (29%)
Ig 340..402 CDD:299845 2/5 (40%)
IG_like 431..502 CDD:214653
Ig 439..502 CDD:299845
FN3 507..601 CDD:238020
FN3 624..714 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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