DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and LOC100006875

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_001345491.5 Gene:LOC100006875 / 100006875 -ID:- Length:718 Species:Danio rerio


Alignment Length:288 Identity:65/288 - (22%)
Similarity:105/288 - (36%) Gaps:53/288 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 LSTGST--LVIKDSRFSLRYDPNSSTYKLQIKDIQETDAGTYTCQVVISTVHKVSAEVKLSVRRP 134
            :..|.|  :...|.||..|...:..|..|.||:|....:|.:  :|.||:..:...::...:.:.
Zfish   331 MGKGETREITYPDERFRDRLQVDKKTGALTIKNITIEHSGDF--KVKISSRRRTQIK
IFCIIIKE 393

  Fly   135 PVISDNSTQSVVASEGSEVQMECYASGYPTPTITWR-----------RENNAILPTDSATYVGNT 188
            ..::....::.|...|:|:|        ....|.||           ::.:.|.|:|....|..|
Zfish   394 EKVTVMEGRTAVLHSGTEIQ--------TNDQIEWRFNTEESPIAEIKDGHKIFPSDGPGGVFRT 450

  Fly   189 ----------LRIKSVKKEDRGTYYCVADNGVSK-GDRR--------NINVEVEFAPVITVPRPR 234
                      |.||:::.|..|.||.:..|..:| .|||        .:.|.|....|:..|   
Zfish   451 TLNLDEKTGSLIIKNIRNEHAGGYYLIIKNRSTKHHDRRFIVKVIEEKVTVMVGDTAVLKSP--- 512

  Fly   235 LGQALQYDMDLECHIEAYPPPAIVWTKD--DIQLANNQHYSISHFATADEYTDSTLRVITVEKRQ 297
              ..:..|..:|...:....| |...||  .|.|::.......:..:.||.|.| |.:..:....
Zfish   513 --AGIHTDDQIEWRFKTDESP-IAEIKDGQKIFLSDGPGGRFKNTQSLDEKTGS-LTIRNIRPEH 573

  Fly   298 YGDYVCKATNRFGEAEARVNLFETIIPV 325
            .|.|.....||  ...|||..|...:.|
Zfish   574 AGGYQLIIKNR--NTGARVKRFTLAVIV 599

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 15/60 (25%)
FR1 37..50 CDD:409353
Ig strand A' 37..42 CDD:409353
Ig strand B 44..51 CDD:409353
CDR1 51..59 CDD:409353
Ig strand C 59..63 CDD:409353
FR2 60..63 CDD:409353
CDR2 67..81 CDD:409353 2/10 (20%)
Ig strand C' 68..72 CDD:409353 65/288 (23%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 9/30 (30%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 1/6 (17%)
CDR3 116..124 CDD:409353 2/7 (29%)
FR4 124..130 CDD:409353 0/5 (0%)
Ig strand G 124..130 CDD:409353 0/5 (0%)
Ig_3 134..208 CDD:404760 19/94 (20%)
Ig strand B 153..157 CDD:409353 1/3 (33%)
Ig strand C 166..170 CDD:409353 1/3 (33%)
Ig strand E 187..191 CDD:409353 2/13 (15%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 2/10 (20%)
Ig 227..318 CDD:416386 22/92 (24%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 2/3 (67%)
Ig strand F 300..305 CDD:409353 1/4 (25%)
LOC100006875XP_001345491.5 Ig 44..124 CDD:299845
Ig 155..248 CDD:299845
Ig 299..385 CDD:299845 15/55 (27%)
IG_like 394..486 CDD:214653 21/99 (21%)
Ig 409..494 CDD:299845 23/92 (25%)
Ig 517..597 CDD:299845 21/83 (25%)
IG_like 600..702 CDD:214653 65/288 (23%)
Ig 619..700 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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