DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lac and dscaml1

DIOPT Version :9

Sequence 1:NP_523713.2 Gene:Lac / 36363 FlyBaseID:FBgn0010238 Length:359 Species:Drosophila melanogaster
Sequence 2:XP_005157551.1 Gene:dscaml1 / 100002762 -ID:- Length:2158 Species:Danio rerio


Alignment Length:399 Identity:103/399 - (25%)
Similarity:138/399 - (34%) Gaps:127/399 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 RTP-TISYITQEQIKDIGGTVEFDCSVQYAKEYNVLFLKTDSDPVFLSTGSTLVIKDSRFSLRYD 90
            |.| |:....|..::  |....|.|.:..|.:..|..:..:.|.|.:..|       :||.|   
Zfish   193 REPYTVRVADQRSMR--GNVAVFKCLIPSAVQEYVSVVSWEKDTVSIVPG-------NRFFL--- 245

  Fly    91 PNSSTYKLQIKDIQETDA-GTYTCQVVISTVHKVSAE------VKLSVRRP----PVISDNSTQS 144
              :|...|.|.|:|:.|| .||.|    .|.||.|.|      .:|||..|    |.:.| |.||
Zfish   246 --TSYGALYISDVQKEDALSTYRC----ITKHKYSGETRQSNGARLSVLDPTESTPSVMD-SFQS 303

  Fly   145 VVASEGSEVQMECYASGYPTPTITWRRENNAILPTDSA-TYVGNTLRIKSVKKEDRGTYYCVADN 208
            .....|..:::.|.|||||.|||.|.::... ||.||. |.....|.|..::.||.|.|.|...|
Zfish   304 GEVQVGRSIELPCIASGYPNPTIRWLKDGRP-LPADSRWTRRLTGLTISDLRLEDSGNYICEVTN 367

  Fly   209 GV-SKGDRRNINV-------------------------EVEFAPVITVP---------------- 231
            .. ||....::||                         .|:.:|..||.                
Zfish   368 SFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHFSI 432

  Fly   232 ------------------------RPRLGQALQ--------------------------YDMDLE 246
                                    ..|.||..|                          ....|.
Zfish   433 QGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLEDGTPRIVSSFSERVVAPGEPFSLM 497

  Fly   247 CHIEAYPPPAIVWTKDDIQLANNQHYSISHFATADEYTDSTLRVITVEKRQYGDYVCKATNRFGE 311
            |..:..|||.|.||.||..:|.:..:..|.:..:|..|.|.:.|...:.|..|.|.|.|.|..|.
Zfish   498 CAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGS 562

  Fly   312 AE--ARVNL 318
            ||  ||:|:
Zfish   563 AEYQARINV 571

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LacNP_523713.2 IG_like 36..131 CDD:214653 28/101 (28%)
FR1 37..50 CDD:409353 2/12 (17%)
Ig strand A' 37..42 CDD:409353 0/4 (0%)
Ig strand B 44..51 CDD:409353 1/6 (17%)
CDR1 51..59 CDD:409353 1/7 (14%)
Ig strand C 59..63 CDD:409353 1/3 (33%)
FR2 60..63 CDD:409353 1/2 (50%)
CDR2 67..81 CDD:409353 3/13 (23%)
Ig strand C' 68..72 CDD:409353 2/3 (67%)
Ig strand C' 79..81 CDD:409353 0/1 (0%)
FR3 84..115 CDD:409353 13/31 (42%)
Ig strand D 84..90 CDD:409353 3/5 (60%)
Ig strand E 94..102 CDD:409353 3/7 (43%)
Ig strand F 108..115 CDD:409353 4/7 (57%)
CDR3 116..124 CDD:409353 3/7 (43%)
FR4 124..130 CDD:409353 2/11 (18%)
Ig strand G 124..130 CDD:409353 2/11 (18%)
Ig_3 134..208 CDD:404760 29/78 (37%)
Ig strand B 153..157 CDD:409353 0/3 (0%)
Ig strand C 166..170 CDD:409353 2/3 (67%)
Ig strand E 187..191 CDD:409353 1/3 (33%)
Ig strand F 201..206 CDD:409353 2/4 (50%)
Ig strand G 215..218 CDD:409353 0/2 (0%)
Ig 227..318 CDD:416386 33/158 (21%)
Ig strand C 256..260 CDD:409353 1/3 (33%)
Ig strand E 286..290 CDD:409353 1/3 (33%)
Ig strand F 300..305 CDD:409353 2/4 (50%)
dscaml1XP_005157551.1 IG_like 112..184 CDD:214653
Ig 112..183 CDD:143165
Ig 194..287 CDD:299845 30/110 (27%)
I-set 302..380 CDD:254352 28/78 (36%)
IGc2 309..370 CDD:197706 24/61 (39%)
IGc2 399..458 CDD:197706 4/58 (7%)
I-set 477..571 CDD:254352 27/93 (29%)
Ig 477..567 CDD:299845 25/89 (28%)
IG_like 581..662 CDD:214653
IGc2 588..646 CDD:197706
Ig 684..751 CDD:143165
IG_like 686..756 CDD:214653
I-set 760..855 CDD:254352
Ig7_DSCAM 778..855 CDD:143211
IG_like 865..956 CDD:214653
Ig 873..963 CDD:299845
FN3 959..1053 CDD:238020
FN3 1060..1157 CDD:238020
FN3 1165..1271 CDD:238020
FN3 1276..1367 CDD:238020
IGc2 1392..1455 CDD:197706
FN3 1486..1559 CDD:238020
FN3 1573..1649 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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