DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dyb and Tusc1

DIOPT Version :9

Sequence 1:	NP_001097287.1	Gene:	Dyb / 36362	FlyBaseID:	FBgn0033739	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_081230.1	Gene:	Tusc1 / 69136	MGIID:	2684283	Length:	205	Species:	Mus musculus

Alignment Length:	210	Identity:	50/210 - (23%)
Similarity:	75/210 - (35%)	Gaps:	66/210 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 DSRATGRSLDSASGTAGT--------------------TMSRVAAASANDEEHRLIARYAARLAQ 412
            :|...||:.:...|..|.                    ..|.:.|..|.||..    |..|||.:
Mouse    24 ESGRLGRAREGGGGGGGVGWRGRAGGARRQLEERFADLAASHLEALRARDERD----RQNARLRE 84

  Fly   413 ENRAPSNLPDNATPIGTDNSRAQRELIAQLESKNKEIMREIARL-----RRQQETEQMAPENPAL 472
            ||          ..:..:|.|.:||        |:.:.|:..||     .|:...|.:||:.||.
Mouse    85 EN----------ARLRLENRRLRRE--------NRSLFRQALRLPGDSGEREAAVETLAPDEPAT 131

  Fly   473 INELRALRQRKGELEGHLGALQDSRRQLMEQLE-----GLMRMLKNQQTASPRSTPNSSPRSGKS 532
            ..:.|.  ..:.|..|...||    |..:|:||     .|:::...||.|.|       |.:.:.
Mouse   132 NRKARG--HGREEEPGSPRAL----RARLEKLEVMYRRALLQLHLEQQGARP-------PGAIEE 183

  Fly   533 PPMPGGA-GILGTSP 546
            ||:...| |:....|
Mouse   184 PPLQETATGLCAHDP 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dyb	NP_001097287.1	EF-hand_2	7..131	CDD:286194
		EF-hand_3	135..223	CDD:286195
		ZZ_dystrophin	232..280	CDD:239074
		Ribosomal_L29	436..482	CDD:279204	13/50 (26%)
Tusc1	NP_081230.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		5/24 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..149		9/37 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..205		8/32 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960