DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dyb and CG3526

DIOPT Version :9

Sequence 1:	NP_001097287.1	Gene:	Dyb / 36362	FlyBaseID:	FBgn0033739	Length:	816	Species:	Drosophila melanogaster
Sequence 2:	NP_726832.2	Gene:	CG3526 / 31277	FlyBaseID:	FBgn0040355	Length:	229	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	50/216 - (23%)
Similarity:	77/216 - (35%)	Gaps:	64/216 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 CSVCHKENFTGFRYRCQRCHAYQLCQECFWHGKTSLNHQNDHEV-----KEYSSYKSPSKQIGHS 293
            |..|.....|.:||:|..|..|.||.:|..:|.::..|..||.:     ::........:.|...
  Fly    32 CDGCGNNRMTFYRYKCLHCLDYDLCSDCKENGVSNGLHSLDHPLQCLMDRDALELHFAGEPIPIL 96

  Fly   294 LRKSFRCVP----------------------EKTVQVLP---RFP-DQPEKTLNLSHIVPPSPLP 332
            ...||.| |                      .:||.:.|   ..| .||....::::.:..|  |
  Fly    97 CADSFTC-PVCGEMGFSVEDLRTHCQDNHRMARTVCICPVCAAVPLSQPSHIAHIANHLMFS--P 158

  Fly   333 SHNGFSDPSGLVHGHHGPHPGLPGQHGLFDRSSTLDSRATGRSLDSASG-TAGTTMSRVAAASAN 396
            ||....||                   :.|.|:|  |:|.|.||...|. ::|:......::|.|
  Fly   159 SHRATGDP-------------------MIDISAT--SQAEGSSLPQNSAVSSGSGAQHTFSSSEN 202

  Fly   397 DEEHRLIARYAARLAQENRAP 417
            .:     .|:   |...||||
  Fly   203 SQ-----VRF---LLPGNRAP 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dyb	NP_001097287.1	EF-hand_2	7..131	CDD:286194
		EF-hand_3	135..223	CDD:286195
		ZZ_dystrophin	232..280	CDD:239074	15/50 (30%)
		Ribosomal_L29	436..482	CDD:279204
CG3526	NP_726832.2	ZZ_PCMF_like	30..78	CDD:239078	15/45 (33%)
CG3526	NP_726832.2	zf-Di19	99..149	CDD:283297	10/50 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12268
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100